Planterosomes, term “PLANTERO” means plant while “SOME” means celllike. A novel emerging technique applied to phytopharmaceutical for the enhancement of bioavailability of herbal extract for medicinal applications. Since the two major limiting factors for molecules to pass the biological membrane for their absorption in the blood stream mainly includes lipid solubility and molecular sizes. Ther...

the purpose of this study was to optimize a method for the encapsulation of p5 peptide, a new designed peptide containing mhc class i epitopes from rat her2/neu protein, into liposomes as an approach for breast cancer vaccine formulation. the efficiency of liposomal encapsulation of peptides is generally low and development of an optimized method to increase encapsulation efficiency is a big ch...

Plant extract compounds have various industrial applications as well some limitations. However, the encapsulation of them through different techniques is known a way for optimizing their physicochemical properties, biological activities, and effectivity to improve shelf-life foods. In this review, latest food cyclodextrin inclusion complexes, liposomes, electrospinning encapsulating methods pla...

The purpose of this study was to optimize a method for the encapsulation of P5 peptide, a new designed peptide containing MHC class I epitopes from rat HER2/neu protein, into liposomes as an approach for breast cancer vaccine formulation. The efficiency of liposomal encapsulation of peptides is generally low and development of an optimized method to increase encapsulation efficiency is a big ch...

Due to the multiple hydroxyl groups in its structure, hydroxytyrosol (HT) is very sensitive to air and light and has very strong instability and hydrophilicity that affect its biological activity. This study attempted to prepare liposomes containing water-soluble HT to improve the bioavailability and biocompatibility of the target drug. The preparation process factors (temperature, mass ratio o...

Liposomes are the most advance formulation for targeting and controlled drug delivery system. These liposomes generally administered by intra-venous route. In this work liposome was prepared using thin film hydration method. The formulated is evaluated or characterised zeta sizer, Encapsulation efficiency, Entrapment vitro release. Main things which used of Diclofenac sodium, it having anti-inf...

Introduction: Lucid morinda (L) A medium-sized evergreen tree of the Morinda genus, Benth (M. lucida, Rubiaceae) is a tropical West African rainforest plant that also known as Brimstone tree. In several nations, it utilized in traditional medicine to cure variety human ailments. Phytosomes are freshly developed herbal formulations have superior bioavailability and effects than phyto molecules o...

Curcumin, a naturally occurring lipophilic molecule can exert multiple and diverse bioactivities. However, its limited aqueous solubility and extensive presystemic metabolism restrict its bioavailability. Curcumin phytosomes were prepared by a simple solvent evaporation method where free flowing powder was obtained in addition to a newly developed semisolid formulation to increase curcumin cont...

Over the past four decades, the research focused in the development of new liposomal drug delivery systems exponentially grew as a result of their proven efficacy in carrying pharmacological active molecules to target specific sites. In fact, the drug loading into liposomes both increases the drug’s bioavailability through the prevention of unfavourable chemical reactions triggered by enzymatic...

Phytomedicines are used worldwide by human being from ancient times. Herbal drugs are becoming more popular in the modern world for their application to cure variety of diseases with less toxic effects and better therapeutic effects. However these medicines suffer from certain limitation such as toxicity, stability issues, poor bioavailability and patient compliance. To minimize these problems ...