نتایج جستجو برای: balb c mice

تعداد نتایج: 1398969  

Journal: :journal of north khorasan university of medical sciences 2022

The Effect of Different Ozone Concentrations on the Expression β-catenin and HIF-I Genes in Colon Tissue BALB/c Mice Treated with Azoxymethane/dextran Sodium Sulfate

Journal: :Infection and immunity 2002
Lisa Shubitz Tao Peng Robert Perrill Julie Simons Kris Orsborn John N Galgiani

Subcutaneous vaccination with recombinant antigen 2/PRA (rAg2/PRA) protected BALB/c mice against intranasal infection with Coccidioides immitis. Subcutaneously vaccinated C57BL/6 mice and intranasally vaccinated BALB/c mice were protected against larger numbers of infecting spores. Weight loss correlated with lethality, but histologic appearance did not. These studies support rAg2/PRA vaccinati...

2011
Karen J. Bryson Owain R. Millington Thabang Mokgethi H. Adrienne McGachy Frank Brombacher James Alexander

Immunologically intact BALB/c mice infected with Leishmania mexicana develop non-healing progressively growing lesions associated with a biased Th2 response while similarly infected IL-4Rα-deficient mice fail to develop lesions and develop a robust Th1 response. In order to determine the functional target(s) for IL-4/IL-13 inducing non-healing disease, the course of L. mexicana infection was mo...

Journal: :Infection and immunity 2001
S Schilling N Glaichenhaus

Susceptibility of BALB/c mice to Leishmania major depends on the early production of IL-4 by CD4(+) T cells which react to the parasite LACK antigen. Here, we show that LACK-specific cells are rapidly recruited to the site of infection and favor the early dissemination of L. major to the internal organs.

Journal: :Journal of virology 1974
S A Aaronson C Y Dunn

A sensitive biological assay has been developed for studying the frequency of virus induction from mouse cells containing poorly infectious endogenous C-type viruses. A low spontaneous frequency of virus activation of one but not a second endogenous virus of BALB/c cells has been demonstrated. The resistance of BALB/c cells to superinfection by the more inducible virus appears to be absolute, w...

2005
Sophie Koutouzov Alexis Mathian Arthur Weinberg Mike Gallegos Jacques Banchereau

Journal: :iranian biomedical journal 0
آمینا کریمی نیا amina kariminia سوسن کبودیان اردستانی sussan k. ardestani نرگس السادات اردستانی nargess al-sadat ardestani حوریه سپهری houri sepehry هایده دارابی haideh darabi

it is now well documented that interferon gamma (ifn-γ) is the indispensable cytokine for inducing protective immunity against experimental and human cutaneous leishmaniaisis. the importance of ifn-γ receptor (ifn-γr) has also been studied. in the present study, we made attempts to find out whether l. major infection is able to alter the expression of ifn-γr in vivo. in addition, we studied the...

Journal: :iranian journal of public health 0
m taran m mohebali j esmaeli

background: recent circumstantial evidences are suggesting that an increasing number of iranian patients with cu­taneous leishmaniasis are unresponsive to meglumine antimoniate (glucantime®). pistacia atlantica is native plant in iran (central, western, and eastern regions). gum obtained pistacia atlantica has been reported to possess consid­erable in vitro antimicrobial activity. in this study...

Journal: :iranian journal of allergy, asthma and immunology 0
sedighe ebrahimpoor immunology department, pasteur institute of iran, tehran, ir-iran saeed-reza pakzad food and drugs control laboratory and research centre, ministry of health and medical education, tehran, ir-iran soheila ajdary immunology department, pasteur institute of iran, tehran, ir-iran

it is well accepted that in experimental model of leishmania major infection, balb/c mice mount a th2 response and produce igg1 predominantly whereas c57bl/6mice enhance th1 response with the biased production of igg2a antibodies. therefore, screening for parasite antigens on the basis of reactivity with sera from infected susceptible or resistant mice might be used for the identification of th...

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