background: dermatophagoides farinae and dermatophagoides pteronyssinus are house dust mites (hdm) that they cause severe asthma and allergic symptoms. tropomyosin protein plays an important role in mentioned immune and allergic reactions to hdms. here, tropomyosin protein from dermatophagoides spp. was comprehensively screened in silico for its allergenicity, antigenicity and similarity/conser...

The dependent tumors exhibited minor chromosomal changes and thyroglobulin antigenicity similar to that of normal rat thyroid. The transitional tumors exhibited moderate chromosomal alterations and practically no thyroglobulin antigenicity. The autonomous tumors exhibited severe chromosomal alteration, numerically and/or structurally, and no detectable immunogenicity related to thyroglobulin. A...

Mutation in the hepatitis B virus surface antigen (HBsAg) may affect the efficiency of diagnostic immunoassays or success of vaccinations using HBsAg. Thus, antigenicity and immunogenicity analyses of the mutated HBsAg are necessary to develop novel diagnostic tools and efficient vaccinations. Here, the in vitro antigenicity of three wild-type HBsAg open reading frames (ORFs) (adr4, W1S [subtyp...

The recent appearance and growth of new SARS-CoV-2 variants represent a major challenge for the control COVID-19 pandemic. These concern contain mutations affecting antigenicity, which raises concerns on their possible impact human immune response to virus vaccine efficacy against them.

The effects of physical and enzymatic treatments of gelatin on the gelatin-antigelatin reaction have been presented. The data obtained indicate that the gelatin-antigelatin reaction is indeed a specific one. It appears that a definite limiting molecular size and specific molecular pattern of this molecular unit are necessary for reaction with antibody.