background: in current study, chemical composition and antibacterial activity of leaves and flowers essential oils of origanum vulgare ssp. gracile against four food-borne pathogens including  escherichia coli, listeria monocytogenes, salmonella thyphimurium and staphylococcus aureus were examined. methods: the different organs (leaves and flowers) of o. vulgare ssp. gracile were harvested at f...

BACKGROUND Influenza viruses cause serious infections that can be prevented or treated using vaccines or antiviral agents, respectively. While vaccines are effective, they have a number of limitations, and influenza strains resistant to currently available anti-influenza drugs are increasingly isolated. This necessitates the exploration of novel anti-influenza therapies. METHODOLOGY/PRINCIPAL...

Influenza A viruses (IAVs) cause seasonal pandemics and epidemics with high morbidity and mortality, which calls for effective anti-IAV agents. The glycoprotein hemagglutinin of influenza virus plays a crucial role in the initial stage of virus infection, making it a potential target for anti-influenza therapeutics development. Here we found that quercetin inhibited influenza infection with a w...

conclusions from the results, it was concluded that agricultural lands around pakistan council of scientific and industrial research (pcsir) campus lahore were rich sources of industrially important streptomyces, especially s. avermitilis. results the 10 selected isolates were identified as the avermectin-producing strain by fermentation and characterized on isp2 medium for aerial and reverse s...

background & objectives: nanotechnology is one of great important part of technology. nanoparticles can be used in different applications for industrial, medical, military and personal use. the objectives of this study were preparation of polystyrene/zno nanocomposite films via a simple method and investigation of antibacterial activity of them. methods: polystyrene /zno nanoparticle (ps/n...

Influenza causes respiratory infections and poses health risks to humans and animals; its effects are complicated by increasing resistance to existing anti-influenza viral agents. Therefore, novel therapeutic approaches against influenza virus infection are required. Psoraleae semen has been widely used in traditional medicine in Korea, Taiwan, China, and Japan for treating and preventing vario...

Despite the best efforts of influenza scientists, companies and health officials to prepare for the next pandemic, most of the world's people will not have access to affordable supplies of vaccines and antiviral agents. They will have to rely on 19th century public health 'technologies' to see them through. In the 21st century, science ought to be able to provide something better. Influenza sci...

The urgent need of neuraminidase inhibitors (NI) has provided an impetus for understanding the structure requisite at molecular level. Our search for selective inhibitors of neuraminidase has led to the identification of pharmacophoric requirements at various positions around acyl thiourea pharmacophore. The main objective of present study is to develop selective NI, with least toxicity and dru...

herbal medicine can be a valuable source of assistance for traditional medicine. there are a number of herbs that can be used in conjunction with modern medicine. herbs can also be taken to aid recovery from serious diseases. although one should never aim to treat diseases such as cardiovascular disease solely with herbal medicine, the value of herbs used in tandem with modern medicine cannot b...