Generating aircraft position, velocity, and attitude along a reference trajectory is useful in many path mission planning applications. In applications simulating an inertial navigation system the body-frame accelerations angular rates are also required. This work presents method for generating smoothed continuous-curvature from series of waypoints using line, arc, clothoid, Fermat spiral segme...

A comprehensive, systems level understanding of cell signaling networks requires methods to efficiently assay multiple signaling species, at the level of single cells, responding to a variety of stimulation protocols. Here we describe a microfluidic device that enables quantitative interrogation of signaling networks in thousands of individual cells using immunofluorescence-based readouts. The ...

A new teaching experience is presented in this paper. The author introduces purposefully more advanced analytical methods in his engineering technology curricula. The author integrates mathematical explanations and physical insights into technology courses such as analog communication systems, digital communications, and electric power generation, transmission, and distribution. This instructio...

RESEARCH SUMMARY: This research will be integral to development of sampling and analytical methods used to assess exposures to asphalt fumes and specific irritants and genotoxins. Laboratory research will be useful in designing better worker exposure protocols, identifying specific biomarkers to assess a worker's true exposure, and designing animal studies to evaluate physiological and toxicolo...

A new approach to signal processing of analytical time-domain data is presented. It consists in identifying the types of noise, characterizing them, and subsequently subtracting them from the otherwise unprocessed data set. The algorithms have been successfully applied to three classes of noise commonly found in analytical signals: spikes, ripples, and baseline drift. Traditional filters have b...