We study the planning of a multi-modal transportation system with perishable products, demand uncertainty and repositioning empty Returnable Transport Items (RTIs). propose rolling horizon framework where we periodically re-optimize. As such, relevant responses actions to new occurred are taken, possible updates plans can be made. Our considers customer demand, formulated as Scenario-based Two-...

BACKGROUND Prone breast positioning reduces skin reaction and heart and lung dose, but may also reduce radiation dose to axillary lymph nodes (ALNs). METHODS Women with early stage breast cancer treated with whole breast irradiation (WBI) in the prone position were identified. Patients treated in the supine position were matched for treating physician, laterality, and fractionation. Ipsilater...

This paper deals with the dial-a-ride problem transfer, where a set of customer demands are divided into two different regions, such as pickup and delivery nodes must not be in same region for given request. Two vehicles needed to meet demand which implies synchronization process between transfer point called central hub. In this paper, we provide solution method based on an adaptive large neig...

Despite the good responses of patients (pts) with stage III breast cancer to neoadjuvant chemotherapy (NAC), most eventually relapse and have a poor prognosis. We investigated the prognostic indicators in pts with stage III breast cancer treated with NAC, using epirubicin and/or docetaxel. A total of 22 women with stage III breast cancer underwent NAC between January 2005 and May 2011. The regi...

This paper introduces the fish feed production routing problem (FFPRP) faced by Norwegian salmon producers. The FFPRP is comprised of a scheduling and rich vehicle (VRP) thus denotes variant integrated problem. We present discrete time mixed integer programming (MIP) model FFPRP. Specifically, incorporates multi-product, multi-trip, multi-depot setting, where orders are produced at lines factor...

In this paper, we address a multi-objective residential waste collection problem with an integrated territory planning and vehicle routing approach. Dividing the into territories enables drivers to carry out same route every week so they get familiar it residents put their bins at appropriate time. Another benefit is reduce computation time for large problems, since complex characteristics of i...

Research on metaheuristics has focused (novel) algorithmic development and competitive testing, both of which have been frequently argued to yield little generalizable knowledge. The main goal this paper is promote meta-analysis — a systematic statistical examination that combines the results several independent studies as more suitable way obtain problem- implementation-independent insights me...

This article applies the concept of classroom community to asynchronous learning networks (ALNs) by taking on the issue of how best to design and implement a course that fosters community among learners who are physically separated from each other. The following factors that can influence sense of community among distant learners are examined: student–instructor ratio, transactional distance, s...

In this paper, a two-stage stochastic mathematical model is developed for an asset protection routing problem under wildfire. The main aim of study to reduce the negative impact Some parameters, such as travel and service times, obtaining profit by protecting asset, upper bounds time windows, are considered parameters. Generating proper scenarios uncertain parameters has large on accuracy obtai...