glutathione, considered to be the master antioxidant (ao), is the most-important redox regulator that controls in therapeutic considerations for the adjunctive use of glutathione in management of periodontitis, in limiting the tissue damage associated with oxidative stress, and enhancing wound healing cannot beunderestimated, but need to be evaluated further through multi-centered randomized co...

Current evidence suggests that periodontal infection may aggravate diabetes control. The aim of this study was to determine the changes in the frequency with which Porphyromonas gingivalis, Tannerella forsythia, Treponema denticola and Aggregatibacter actinomycetemcomitans were detected in patients with diabetes with the use of non-surgical therapy plus azithromycin in a randomized clinical tri...

BACKGROUND AND OBJECTIVE The evidence for the efficacy of the adjunctive use of platelet-rich plasma (PRP) in periodontal intraosseous defects has not been systematically evaluated. The objective of this review was to address the focused question, 'What is the efficacy, with respect to clinical, radiographical and patient-centred outcomes, of combinations of PRP with other therapeutic bioactive...

The aim was to assess whether or not photodynamic therapy (PDT) with adjunctive scaling-and-root-planing (SRP) is effective in the treatment of periodontitis under immunocompromised conditions. PubMed/Medline and Google-Scholar databases were searched from 1967 to May 2013 using various key words. Six studies (five experimental and one clinical) were included. In the clinical study, SRP with PD...

systemic antibiotics and locally applied antimicrobial agents have been suggested to enhance clinical parameters. patients exhibiting aggressive periodontitis in particular benefit from adjunctive antibiotic therapy. the purpose of this investigation was to evaluate the effect of local antibiotic therapy with metronidazole adjunctively to scaling and root planning (srp) in the treatment of aggr...

Laser is considered basically effective for treating periodontal diseases because of its excellent physical properties namely ablation, hemostasis, bacterial killing and cell stimulation. The current laser application mainly used for the treatment of periodontitis is high-power laser ablation (HLLT). Laser ablation of diseased periodontal tissues using the HLLT is widely performed, partly expec...

Patients with Type 2 Diabetes mellitus (T2DM) were more prone to suffer from periodontitis due unique alteration in host immune response. Application of curcumin oral gel as adjunctive therapy was expected improve periodontal condition its anti-inflammatory properties. The objective this study evaluate the effect on inflammation patients T2DM. Sixteen pockets (n=16) T2DM administered using blun...

Periodontal disease is a term that encompasses several pathological conditions affecting the tooth supporting structures. Periodontitis is an inflammatory disease of the supporting tissues of the teeth caused by groups of specific microorganisms. Aggressive forms of periodontitis can be localized or generalized. Various drug delivery systems are used to treat this condition. Intra pocket dental...

The primary purpose of irrigation is to nonspecifically reduce the bacteria and their by-products that lead to the initiation or progression of periodontal diseases. Supragingival irrigation allows for the disruption and dilution of marginal bacteria and their by-products which helps to prevent or treat gingivitis. Subgingival irrigation interferes with the complex ecosystem required for the in...