Herein we describe a catalyst-free, one-pot procedure employing an Ugi-4CR between propargyl glycine, functionalised 2-azidoanilines, different isocyanides and aldehydes, followed by a thermal azide-alkyne Huisgen cycloaddition to generate a 14-member set of amino-benzotriazolodiazocine-bearing dipeptides with multiple points of diversification and high atom economy. These structures were deriv...

Young's modulus and internal friction of the V-4Ti-4Cr alloy with different hydrogen content were studied in temperature range 100 − 300 К at oscillation frequencies about kHz. It is shown that hydrogenation gives rise to a minimum dependence due precipitation/dissolution vanadium monohydride particles, relaxation peak spectrum temperatures 140 К, which can be associated Snoek-type caused by Ti...

The aim of this paper is to investigate the WC-10Co-4Cr coatings reinforced with 5 % and 10 yttria-stabilized zirconia (Y2O3/ZrO2; YSZ) nanoparticles deposited on CA6NM turbine steel by using high-velocity oxy-fuel (HVOF) thermal spraying technique. In HVOF technique, hot jet semi-solid particles strikes against workpiece creates a layer coating varying thickness substrate material. fabricated ...

Nowadays, application of cermet coatings deposited by High-Velocity Oxygen-Fuel (HVOF) has received considerable attention in a variety of industries. Carbide coatings have high surface roughness, so it is essential to grind the coated surface. The present investigation studied the effect of simultaneous changes in the grinding parameters including the depth of cut, feed rate and cutting sp...

Article history: Received on: 03/02/2013 Revised on: 20/02/2013 Accepted on: 05/03/2013 Available online: 30/03/2013 An efficient and rapid synthesis of novel anti-inflammatory and antimicrobial agents using 4-aminoantipyrine, nicotinic acid, ethylisocyanoacetate and substituted aldehydes via Ugi four component reaction (Ugi-4CR) protocol under microwave irradiation in presence of Fluorite as a...

A series of novel stereochemically pure derivatives of the investigative broad-spectrum anticonvulsant ADD408003 was designed and synthesized. Five-center four-component (U-5C-4CR) and four-center three-component (U-4C-3CR) variants of Ugi reaction were used in the key step of the synthetic pathways. The compounds obtained were evaluated for the anticonvulsant activitiy in the maximal electrosh...