alkylation of various nucleophiles (HA) with alcohols (ROH) to give RA, utilizing the redox system of diethyl azodicarboxylate (DEAD)–triphenylphosphine (TPP) (Fig. 1). Without any prerequisite activation of the alcohol, it is a unique alkylation reaction and widely applied to various phases of organic synthesis. However, the reaction has a serious limitation; the acidic hydrogen in HA has to h...

Abstract Introduction Foreign body injections were first used, in the form of mineral oil, 1899 to augment men post orchidectomy for tuberculous orchitis. In 1940s and 1950s, documented cases purposeful penile foreign started be reported as “penile paraffinomas.” Their surgical correction is challenging due risk skin necrosis wound breakdown. Objective The aim study present a large case series ...

0. Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 439 1. The deformation problem . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 448 1.1. Formulation of the problem . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 448 1.2. Changing the da...

(1) The Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, (2) Center for Reproductive Sciences, (3) Department of Urology, (4) Department of Epidemiology and Biostatistics (5) Division of Hematology and Oncology, Department of Medicine, (6) Department of Pathology and (7) UCSF – Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, S...

quently occurring chronic diseases in puberty. It afflicts millions of individuals worldwide, and its prevalence and incidence continue to rise annually. This disease results from selective destruction of the insulin-producing b cells in the pancreatic islets, and is primarily a T cell-mediated autoimmune disease directed against one or more b cell autoantigens. T cells specific for islet b cel...

We report the high-quality draft genome sequence of Xanthomonas sacchari strain LMG 476, isolated from sugarcane. The genome comparison of this strain with a previously sequenced X. sacchari strain isolated from a distinct environmental source should provide further insights into the adaptation of this species to different habitats and its evolution.

Ocular disease caused by herpes simplex virus (HSV) 1 ranges in severity from a self-limiting blepharitis, conjunctivitis, or dendritic keratitis to a disciform stromal edema and necrotizing stromal keratitis that can cause blindness. Herpes keratitis and stromal disease are distinct, readily differentiable clinical entities that can be studied in animal models. In pure dendritic herpes keratit...