OBJECTIVES Dermatophytes, belonging to genera including Trichophyton, Epidermophyton, and Microsporum, are the causative agents of superficial fungal infections, prevalences of which are estimated to be as high as 25% in the worldwide population. This study evaluated the activity of topical formulations of NVC-422 (sodium 2-[dichloroamino]-2-methylpropane-1-sulfonate), the lead compound in a ne...

The integration is carried out in the reference frame in which the spatial components of P, are zero and the dimensionless quantities cr = l4/222 and c=Fp/m are introduced. The real part of 8M is obtained by straightforward integration with absolute value signs placed on the argument of the logarithm: Re 5M = (3g2/162r2) m( —1+2n2+ (1+3422 2c24+ (422—1)/e') in~+ ccp (2422—7) (4—c22)—*' Xtan-'a(...

Rotavirus infection is the major cause of fatal diarrhea among children younger than five years. We aimed to determine the frequency of rotavirus infection according to age, gender and month of the year. From April 2008 through March 2013, 3,106 fresh stool specimens of children under the age of 16 years were tested for rotavirus antigen, and rotavirus antigen was detected as positive in 422 (1...

Na+ and Cl(-)-coupled glycine transporters control the availability of glycine neurotransmitter in the synaptic cleft of inhibitory glycinergic pathways. In this report, we have investigated the involvement of the second intracellular loop of the neuronal glycine transporter 2 (GLYT2) on the protein conformational equilibrium and the regulation by 4alpha-phorbol 12 myristate 13-acetate (PMA). B...

3,371,997 3/1968 Jordan et al ........................ 423/450 4,013,420 3/1977 Cheng ................................. 422/156 4,084,024 4/1978 Schumacher ....................... 423/350 4,154,870 5/1979 Wakefield ....................... 423/350 X 4,241,022 12/1980 Kraus et al. ......................... 422/156 4,292,344 7/1981 McHale .......................... 423/349 X 4,314,525 2/1982 Hsu e...

The rat heart contains an abundant cytosolic protein which binds long chain fatty acids. We have determined its primary structure by Edman degradation of peptides generated from chymotryptic, tryptic, and elastase digestions. This polypeptide (Mr = 14,992) contains 134 amino acids and has a blocked (acetylated) NH2 terminus. The sequence of rat heart fatty acid-binding protein (FABP) is remarka...

The Advisory Committee on Existing Chemicals (BUA) of the Federal Republic of Germany convened a panel with expertise in reproductive and developmental toxicology to evaluate the OECD Screening Tests 421 (Reproduction/Developmental Toxicity Screening Test) and 422 (Combined Repeated Dose Toxicity Study with the Reproduction/Developmental Toxicity Screening Test) with respect to their ability to...

INTRODUCTION .......................................................... 409 PURIFUICATION OF PLASMID DEOXYRIBONUCLEIC ACID FROM STREPTCOCCI ......................................................... 412 CONJUGATION AND PLASMID TRANSFER ......... ........................ 413 SEX PHEROMONES IN STREPTOCOCCUS FAECALIS ....... ................ 415 RESISTANCE TRANSFER IN THE ABSENCE OF PLASMID DEOXYRI...