We have discovered that phenyl tosylates can be used to arylate pyridines at the C3-position using a Pd(OAc)2-1,10-phenanthroline catalyst system. We also discovered that the reaction of 4-methylpyridine with naphthyl tosylates occurred on the methyl group instead of at the C3-position.

Deacetoxylation of the oxo-centered triruthenium acetate cluster by acetyl chloride or triethylsilyl chloride led to the formation of a versatile precursor [Ru(3)O(OAc)(5)(Cl)(4-methylpyridine)(2)(CNt-Bu)], whose chloro ligand was readily substituted by other bridging ligands, i.e. alkoxides, carboxylates or sulfides.

A convergent synthesis of 5-acetyl-4-(4'-alkyloxyphenyl)-3-cyano-6-methylpyridine-2(1H)-thiones and their derivatives S-alkylthiopyridines was described. The main steps towards the formation of the title compounds involve the reactions of 4-alkyloxybenzaldehydes with 2-cyanothioacetamide to afford 2-cyano-3(4'-alkyloxyphenyl)prop-2-enethioamides which then reacted with acetylacetone prior to th...

Multicomponent reactions involving azines (4-methylpyridine, isoquinoline and N-methyl imidazole) and acetylenic ester were undertaken in the presence of CH compound such as 2-furoyl trifluoroacetone(4,4,4-trifluoro-1-thiophen-2-yl-butan-1,3-dione) to generate enaminoesters as stable 1,4-diionic compounds in high yields.

The influence of temperature on the proton location in hydrogen bonds has been systematically studied by neutron diffraction in only a few crystal structures. Two of these are the 1:1 complex of urea - phosphoric acid with an OHO hydrogen bond and 4-methylpyridine -pentachlorophenol with an OHN hydrogen bond. Based on these earlier determined crystal structures the potential energy surface (PES...

The quasi-Werner-type copper(II) complex, [Cu(PF(6))(2)(4-mepy)(4)] (1), in which 4-mepy is the 4-methylpyridine ligand, has flexible and polar axial bonds of Cu-PF(6). Flexibility of the Cu-PF(6) bonds induces diverse and unprecedented guest-inclusion structures, such as {[Cu(PF(6))(2)(4-mepy)(4)][Cu(PF(6))(4-mepy)(4)(acetone)]·PF(6)·4acetone} (γ-1⊃2.5acetone), {[Cu(PF(6))(2)(4-mepy)(4)][Cu(PF...