We report a family with co-occurring disorders including neuroblastoma in the first child conceived by in-vitro fertilization with history of sodium valproate use by the mother during pregnancy and mosaic trisomy 22 in the third child. We discuss the possibility of an association between the disorders but conclude that no firm aetiological connection can be established between the different dis...

Three papers in the Journal this month consider issues related to measuring, understanding and treating mental ill health in childhood. Baron-Cohen et al (pp. 500–509) undertook a study to establish the prevalence of autism-spectrum conditions in Cambridgeshire using two case ascertainment methods. First, a survey of individuals on the Special Educational Needs register and second, a screening ...

AIMS This study evaluated the effect of anaerobic digestion at 22, 38 and 55°C on odour, coliforms and chlortetracycline (CTC) in swine manure or monensin (MON) in cattle manure. METHODS AND RESULTS Swine or cattle were fed the respective growth promotant, manure was collected, and 2-l laboratory methane digesters were established at the various temperatures and sampled over 25 or 28 days. Af...

Department of Building and Industrial Production Engineering, University CEU Cardenal Herrera Avda.Seminario s/n, 46113, Moncada, Valencia, Spain Email: [email protected], [email protected], [email protected], [email protected] (*corresponding author), web page: http://www.uchceu.es Departamento de Ingeniería Mecánica y de Materiales, Universidad Politécnica de Vale...

The relationship between maturation of the small intestine and change in mucosal immune activity was examined in the DA rat during the weaning period from 12 to 30 days. Two stages of jejunal maturation were observed: an initial stage of morphological development and crypt proliferation (days 12 to 22), followed by a period of stabilisation (days 24 to 30). By day 22 of the initial phase, villi...

Introduction: The impact history of the solar system remains controversial. Early investigation of lunar samples, returned by Apollo astronauts, led to the 'Late Heavy Bombardment' (LHB) concept [1,2] which hypothesized a sharp increase in bolide flux centered around ~3.9 Ga. Evidence for this cataclysm was first derived from whole-rock U-Pb and Rb-Sr ages [2] but subsequently more on 40 Ar-39 ...