The effects of genistein on 30-day survival and delayed lung injury were examined in C57BL/6J female mice. A single subcutaneous injection of vehicle (PEG-400) or genistein (200 mg/kg) was administered 24 h before total body irradiation (7.75 Gy (60)Co, 0.6 Gy/min). Experimental groups were: No treatment + Sham (NC), Vehicle + Sham (VC), Genistein + Sham (GC), Radiation only (NR), Vehicle + Rad...

recoiling forces of excised cat lungs. J Appl Physiol 14: 905-908, 1959 35. 30. Hauge A, Bo G, Waaler BA: Interrelations between pulmonary liquid volumes and lung compliance. J Appl Physiol 38: 608-614, 1975 31. Lenfant C, Howell BJ: Cardiovascular adjustments in dogs during 36. continuous pressure breathing. J Appl Physiol 14: 425-428, 1960 32. Staub NC, Nagano H, Pearce ML: Pulmonary edema in...

Obesity is linked to increased risk of colon cancer, currently the third most common cancer. Consequently rising levels of obesity worldwide are likely to significantly impact on obesityrelated colon cancers in the decades to come. Understanding the molecular mechanisms whereby obesity increases colon cancer risk is thus a focus for research to inform strategies to prevent the increasing trend ...

Paraquat is a commonly used herbicide in many countries which can lead to systematic poisoning on exposure, In this study, paraquat (PQ)-induced changes in the expression of Cyclooxygenase-2 (COX-2) along with biochemical and histopathological changes in the lungs, liver and kidneys were studied. Twenty four male Wistar rats (180-200 g) were exposed either against saline as control group or var...

The best entertainment for the younger generation now is given in the form of Social Networking sites. The Online Social Networks (OSN) mainly helps an individual to connect with their friends, family and the society online in order to gather and share new experiences with others. Nowa-days, the OSNs are facing the problem of the people posting the indecent messages on any individual's wall whi...

We present a brief report on the factorization of RSA-180, currently smallest unfactored RSA number. We show that the numbers of similar size could be factored in a reasonable time at home using open source factoring software running on a few Intel Core i7 PCs.

The 180 models collected in this paper are produced by sampling and wrapping point sets on tubes. The surfaces are represented as triangulated 2-manifolds and available as stlfiles from the author’s web site at www.cs.duke.edu/ edels. Each tube is obtained by thickening a circle or a smooth torus knot, and for some we use the degrees of freedom in the thickening process to encode meaningful inf...

In applications of NMR in inhomogeneous fields, sequences based on the Carr-PurcellMeiboom-Gill (CPMG) sequence play a central role. The standard CPMG sequence consists of an initial 90° excitation pulse, followed by a long string of 180° refocusing pulses. This creates a series of echoes that decay with characteristic relaxation time T2eff. Here we present a modified sequence, the Split-180° s...

Laninamivir octanoate (LO) (Inavir; Daiichi Sankyo, Japan) is an ester prodrug of the neuraminidase inhibitor laninamivir. We previously reported that a prolonged high retention of laninamivir in mouse respiratory tissues was achieved by intranasal administration of LO. In this study, we evaluated intrapulmonary pharmacokinetics both in vivo and in vitro to investigate the potential mechanism i...

Phillipa Caudwell, Catherine Gibbons, Mark Hopkins, Erik Naslund, Neil King, Graham Finlayson and John Blundell* Institute of Psychological Sciences, Faculty of Medicine and Health, University of Leeds, Leeds LS2 9JT, UK Sport, Health, Leisure and Nutrition, Leeds Trinity University College, Brownberrie Lane, Horsforth, Leeds LS18 5HD, UK Clinical Sciences (Division of Surgery), Danderyd Hospit...