The RNA-binding protein YBX1 (Y-box binding protein-1) is an epidermal stem cell function regulator. Loss of expression in keratinocytes results a decrease the proliferative potential progenitors vitro and alterations all lineages vivo. binds 3’UTR multiple targets cells, inhibits translation potent senescence-associated cytokines guarding cells against occurrence senescence, mediates cells' se...

We have expanded the ligand knowledge base for bidentate P,P- and P,N-donor ligands (LKB-PP, Organometallics2008, 31, 1372-1383) by 208 ligands and introduced an additional steric descriptor (nHe8). This expanded knowledge base now captures information on 334 bidentate ligands and has been processed with principal component analysis (PCA) of the descriptors to produce a detailed map of bidentat...

We describe extensive computations which show that Riemann's zeta function f(s) has exactly 200,000,001 zeros of the form a + it in the region 0 < t < 81,702,130.19; all these zeros are simple and he on the line a = j. (This extends a similar result for the first 81,000,001 zeros, established by Brent in Math. Comp., v. 33, 1979, pp. 1361-1372.) Counts of the numbers of Gram blocks of various t...

www.sciencemag.org SCIENCE VOL 334 9 DECEMBER 2011 1317 COVER Scanning electron micrograph of a female Anopheles stephensi mosquito, a transmitter of malaria (proboscis length: ~0.6 millimeters). To drive malaria eradication, new medicines that target all stages of the malaria life cycle are needed. In their study, Meister et al. used thousands of A. stephensi mosquitos to identify chemical cla...

www.sciencemag.org SCIENCE VOL 334 9 DECEMBER 2011 1317 COVER Scanning electron micrograph of a female Anopheles stephensi mosquito, a transmitter of malaria (proboscis length: ~0.6 millimeters). To drive malaria eradication, new medicines that target all stages of the malaria life cycle are needed. In their study, Meister et al. used thousands of A. stephensi mosquitos to identify chemical cla...

Ground-based remotely sensed data were used in two major approaches to estimate crop coefficient and evapotranspiration (ET) over two treatments of limited-irrigation corn in northeastern Colorado. The first approach, known as the reflectance-based crop coefficient, takes advantage of the unique relationship between crop coefficients (Kc) and vegetation indices of agricultural crops. The second...

The subjective estimation of the body dimensions was investigated on 1372 school-children both sexes aged 11-18 years. analysis consistency estimations (selfestimations and mutual estimations) with real values particular traits (stature, weight hand muscle strength) permitted to draw conclusions referring perception morphological diversity, man.