causes fatal septicemia and necrotizing wound infections, especially in patients with hepatic disease, heavy alcohol drinking habits and hemochromatosis. V. vulnificus septicemia is characterized by rapid and fulminant progression, and results in a high mortality rate of over 50%. Several bacterial components have been suggested to be virulence factors of V. vulnificus. Of these, an extracellul...

Kristin M. Hutchinsa, Ryan H. Groenemanb, Eric Reinheimerc, Dale C. Swensona, and Leonard R. MacGillivraya,* aDepartment of Chemistry, University of Iowa, Iowa City, IA 52242-1294, USA, bDepartment of Biological Sciences, Webster University, St. Louis, MO 63119, USA, cDepartment of Chemistry and Biochemistry, W.M. Keck Foundation Center for Molecular Structure, California State University San M...

Non-small cell lung cancer (NSCLC) cells intake and consume glucose at high efficiency by aerobic glycolysis to maintain robust growth resist death. MicroRNAs (miRNAs) have been known play pivotal roles in NSCLC development partly through mediating glycolysis. However, only a few miRNAs experimentally confirmed as critical regulators of NSCLC. TCGA datasets were analyzed screen for differential...

BACKGROUND Standards for school meals were recently introduced in the UK; however, no such standards exist for packed lunches. This study measures the provision and consumption of a range of food types and nutrients in British children's packed lunches and compares the results with the prevailing school meal standards in England. METHODS Cross-sectional survey data was collected from 1294 chi...

Simulation is important in evaluating novel methods when input data is not easily obtainable or specific assumptions are needed. We present , a cophesim software to add the phenotype to generated genotype data prepared with a genetic simulator. The output of can be used as a direct input for cophesim different genome wide association study tools. is available from cophesim . https://bitbucket.o...

Abstract Introduction lective hip and knee joint replacement patients at the East Lancashire Hospitals NHS Trust (ELHT) are required to attend ‘Hip Knee Joint School’. This is an award-winning patient education programme. Pre-pandemic, it was a day hospital dedicated introducing specifics of surgery. takes from process anaesthesia post-operative ward care. Method Due virulent transmission COVID...