INTRODUCTION Oxidative stress is a key factor in the development of the principal comorbidities of obesity. Methylenetetrahydrofolate reductase enzyme (MTHFR) participates in the metabolism of folate with the action of vitamins B6 and B12. The gene of MTHFR may present a single nucleotide polymorphism (SNP) at position 677 (C677T), which can promote homocysteinemia associated to the production ...

The high-performance liquid chromatography (HPLC) method with photodiode array (PDA) and fluorescence (FL) detection for the simultaneous separation and determination of caffeine and water-soluble vitamins is described. The method is relatively rapid: 13 compounds can be analyzed within 30 min: caffeine; ascorbic acid (vitamin C); thiamine (vitamin B1); riboflavin 5-phosphate (FMN, flavin monon...

hydrogels, due to their unique potentials such as high-water content and hydrophilicity are interest for the controlled release of drug molecules. the present study aims to create a controlled-release system through the preparation and characterization of hydrogels based on ph-sensitive polymers such as poly (acrylic acid). poly (acrylic acid), p(aa), hydrogel has been synthesized by radical po...

B-vitamins are micronutrients that play an important role in various cellular processes of organisms, which only synthesized by plants, yeasts, and bacteria. Since animals humans lack the ability to synthesize B-vitamins, supplements vitamins from dietary B-vitamin producing bacteria required. In this study, we, for first time, shed some light on biosynthetic pathways involved folate (vitamin B...

The nutritional quality of zobo tea flavoured with clove and ginger was assessed. One-way analysis variance applied to the data generated. Dehydrated sorrel calyx (zobo) crushed mixed cloves produce four different blends in teabags. moisture ranges from 9.41% - 11.46%. ash, vitamin B9, calcium content 100% were significantly (p < 0.05) higher than others, while iron 80% 20% others. fibre pro...

Folates are soluble B9 vitamins with essential functions in all kingdoms of life—both in organisms that produce these vitamins de novo (fungi, plants, and most microorganisms) and in those that do not (animals). As essential cofactors in one-carbon transfers, different folate species mediate the biosynthesis of multiple biomolecules, including nucleic acids, amino acids, and lipids. Folates als...