The 6,097 blood donors in Seoul area, the 1,883 pregnant women delivered at Severance Hospital and the 5,136 physical examinees were evaluated for VDRL reactivity. Also, the FTA-ABS and TPHA tests were performed on those who were VDRL-positive, and the 19S (IgM)-FTA test were done on the subjects who were reactive for the FTA-ABS and TPHA tests. All the subjects were over the age of 20 and the ...

BACKGROUND Serology is the mainstay for syphilis diagnosis and treatment monitoring. We investigated serological response to treatment of syphilis according to disease stage and HIV status. METHODS A retrospective cohort study of 264 patients with syphilis was conducted, including 90 primary, 133 secondary, 33 latent, and 8 tertiary syphilis cases. Response to treatment as measured by the Ven...

GOAL To describe clinical and laboratory features of human immunodeficiency infection (HIV)-infected patients with neurosyphilis. STUDY DESIGN Retrospective study of 27 consecutive cases of HIV-infected patients with a positive Venereal Disease Research Laboratory (VDRL) in cerebrospinal fluid (CSF). RESULTS Median of age was 36 years and 89% were men. Ten (37%) patients had previous nonneu...

BACKGROUND Syphilis is a preventable cause of foetal loss and congenital disease. Although the VDRL test is an integral part of routine antenatal care in India, little is known about the disease burden in pregnancy in India. Therefore, we carried out a study to determine the prevalence of VDRL positivity and syphilis among pregnant women in Vellore and to audit the management and outcome of VDR...

A urease-based enzyme-linked immunosorbent assay (ELISA) has been developed for the detection of reagin antibodies in serum. Visuwell Reagin (ADI Diagnostics Inc., Rexdale, Ontario, Canada) is a non-treponemal screening test for the serodiagnosis of syphilis which has the benefits of large batch testing, automatability, and objective interpretation of results. Unheated, undiluted sera are incub...

The specific FTA-ABS and TPI tests are too costly and time-consuming to be used as screening procedures for treponemal disease. The VDRL test detects reagin, the antibody amongst others produced in syphilis and yaws and also present in a wide variety of disorders giving the biological false positive reaction. The RPR card test (Portnoy, Garson, and Smith, 1957; Reed, 1965), like the VDRL test, ...

Lumbar puncture in neurologically asymptomatic HIV+ patients is still under debate. There are different criteria for detecting neurosyphilis through cerebrospinal fluid (CSF), especially in cases that are negative through the Venereal Disease Research Laboratory (VDRL), regarding cellularity and protein content. However, a diagnosis of neurosyphilis can still exist despite negative VDRL. Trepon...