نتایج جستجو برای: vascular endothelial growth factor receptor

تعداد نتایج: 2100290  

It is well known that the metabolic factors play an important role in the regulation of angiogenesis. Increased metabolic activity leads to decreased oxygen levels and causes tissue hypoxia. Hypoxia starts different signals to stimulate angiogenesis and promotes oxygen delivery to tissues. It has been suggested that released adenosine from hypoxic tissues plays a vital role in angiogenesis. ...

Journal: :iranian journal of pathology 2015
noushin afshar moghaddam parvin mahsuni diana taheri

background and objectives: angiogenesis is essential for growth and metastasis of solid malignancies. tumor vessel count and expression of vascular endothelial growth factor (vegf), a potent angiogenic factor, have been associated with prognosis. this study was designed to assess vessels density by using cd31 and cd105 (endoglin) and their correlation with expression of vegf and proliferative i...

Journal: :journal of research in medical sciences 0
lei wang shan ji zeneng cheng

background: the effects of the vascular endothelial growth factor (vegf) gene ?2578c/a polymorphism on colorectal cancer (crc) risk have been investigated in some studies; however, the results of these studies were conflicting and ambiguous. therefore, we aimed to do a meta-analysis to investigate the association of vegf ?2578c/a polymorphisms with crc risk from all eligible case-control studie...

Journal: :iranian journal of basic medical sciences 0
kaveh moradi department of anatomy, medical school, tehran university of medical sciences, tehran, iran mehdi abbasi department of anatomy, medical school, tehran university of medical sciences, tehran, iran farid aboulhasani department of anatomy, medical school, tehran university of medical sciences, tehran, iran niloufar abbasi faculty of medicine, tehran medical branch, islamic azad university, iran kehinde adebayo babatunde department of anatomy, medical school, tehran university of medical sciences, tehran, iran fereydoon sargolzaeiaval department of anatomy, faculty of medicine, zahedan university of medical sciences, zahedan, iran

objective(s):although previous studies have confirmed the beneficial effects of human umbilical cord matrix stem cell (hucm) transplantation post myocardial infarction (mi), but this stem cell resource has no potential to induce angiogenesis. in order to achieve the process of angiogenesis and cardiomyocyte regeneration, two required factors for cardiac repair agents were examined namely; hucm ...

Alizadeh, Nastaran, Attarbashi, Saedeh, Bagheri, Sara, Bashardoust, Nazanin, Modabbernia, Shirin,

Introduction: Odontogenic cysts are osteodestructive lesions affecting the jaws. Odontogenic keratocyst is an odontogenic cyst with highly aggressive features. Multicystic ameloblastoma is a benign epithelial odontogenic tumor with more aggressive behavior than dentigerous cyst and odontogenic keratocyst. Invasion and metastasis of tumors require increased blood vessels during tumorigenesis. Th...

Objectives: Vascular endothelial cells play an important role in the regulation of vascular vessels with active substances, such as vascular endothelial growth factor are responsible. The present study tried to investigate the effect of resistance training on the density of old women’s endothelial growth factor. Methods & Materials: Twenty-four postmenopausal women (age Mean&...

Behzad Torkamanipoor Khadijeh Arjomandi Rafsanjani Mitra Mehrazma,

  Background and Objective: Vascular endothelial growth factor (VEGF) and its receptors (VEGF-R1 and R2) are major regulators of angiogenesis. This study was designed to assess serum levels of VEGF and VEGF-R1 and their prognostic significance in newly diagnosed childhood acute leukemia. Materials and Methods: For this purpose, VEGF and VEGF-R1 were determined using enzyme linked immuno-sorba...

Journal: :iranian journal of basic medical sciences 0
zeng li department of pharmacy, anhui medical university, hefei 230032, china bin wang department of pharmacy, xiangnan university, chenzhou 423000, china liang tang department of chirurgery, first affiliated hospital of anhui medical university, hefei 230032, china shuangsheng chen department of pharmacy, anhui medical university, hefei 230032, china department of chirurgery, first affiliated hospital of anhui medical university, hefei 230032, china jun li department of pharmacy, anhui medical university, hefei 230032, china

objective(s): we previously reported a series of quinazoline derivatives as vascular-targeting anticancer agents. in this study, we investigated the mechanism underlying the anti-angiogenic activity of the quinazoline derivative compound 11d. materials and methods: we examined the effects of quinazoline derivative 11d on vascular endothelial growth factor receptor-2 (vegfr2) activation via vegf...

Objective(s): We previously reported a series of quinazoline derivatives as vascular-targeting anticancer agents. In this study, we investigated the mechanism underlying the anti-angiogenic activity of the quinazoline derivative compound 11d. Materials and Methods: We examined the effects of quinazoline derivative 11d on vascular endothelial growth factor receptor-2 (VEGFR2) activation via VEG...

Journal: :Journal of Biological Chemistry 2005

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