Fetal varicella syndrome is a rare condition of the newborn, presenting with cutaneous scars, limb defects, ocular and central nervous system abnormalities. It is due to varicella or zoster developing in the fetus following maternal varicella infection during early pregnancy. We are reporting a case of congenital varicella syndrome following maternal varicella during the 17th week of pregnancy....

Varisella merupakan penyakit yang mudah menular pada manusia, manusia adalah satu-satunya inang ini. Hal ini disebabkan oleh Varicella Zoster Virus, virus termasuk bagian dari alpha-herpes jenis imunogenik. Sebagai endemik akut paling umum menyerang manusia. masalah setiap orang tua hadapi anak-anaknya, dan varicella juga bisa terjadi di dewasa, biasanya dikenal sebagai cacar air. Tujuan peneli...

OBJECTIVE To describe varicella disease in infants since implementation of the varicella vaccination program in the United States. PATIENTS AND METHODS From 1995 to 2008, demographic, clinical, and epidemiologic data on cases of varicella in infants were collected prospectively through a community-based active surveillance project. We examined disease patterns for infants in 2 age groups: 0 t...

OBJECTIVE To evaluate the cost-effectiveness of routine antenatal varicella serologic screening of pregnant women with negative or indeterminate varicella histories. METHODS Routine antenatal varicella screening was evaluated using a decision analytic model. Outcomes were varicella cases, deaths, and life-years. Probabilities were derived from the literature, and sensitivity analysis was perf...

BACKGROUND Varicella has an important impact on public health. Starting in 2004 in Taiwan, nationwide free varicella vaccinations were given to 1-year-old children. METHODS Our study investigated the epidemiological characteristics of varicella from 2000 to 2008, and assessed the change of varicella epidemiology after the mass varicella immunization. ICD-9-CM codes related to varicella or chi...

It has been estimated that varicella complications occur in 5% to 10% of healthy children. Complications include skin and soft tissue infections, group A streptococcal infections, otitis media, pneumonia, and encephalitis. Between 0.2% and 1.5% of Canadian children with varicella are admitted to hospital. Maternal varicella during the first and second trimesters of pregnancy can lead to congeni...

Because of the severe complications that may result from varicella zoster virus (VZV) infection following renal transplantation (Tx), transplanted varicella-susceptible children exposed to varicella are typically given varicella zoster immunoglobulin (VZIG) as prophylaxis or are admitted and treated with parenteral acyclovir if VZIG prophylaxis fails. As both VZIG and hospitalization are costly...

CONTEXT Several varicella vaccines are available worldwide. Countries with a varicella vaccination program use 1- or 2-dose schedules. OBJECTIVE We examined postlicensure estimates of varicella vaccine effectiveness (VE) among healthy children. DATA SOURCES Systematic review and descriptive and meta-analysis of Medline, Embase, Cochrane libraries, and CINAHL databases for reports published ...

CONTEXT Apparent second episodes of varicella are reported in immunocompetent hosts, but laboratory confirmation of prior immune status has rarely been possible. OBJECTIVE To evaluate adult patients with varicella who claimed to have had previous varicella to determine whether they had true second episodes or primary cases with inaccurate clinical histories. DESIGN Adult subjects with varic...

Whether reexposure of varicella-immune persons to varicella-zoster virus would protect against or predispose to development of zoster was analyzed. The rate of zoster in 511 leukemic recipients of varicella vaccine who had 1 or > 1 dose of varicella vaccine and in those who did or did not have a household exposure to varicella was determined. A Kaplan-Meier life-table analysis revealed that the...