نتایج جستجو برای: v34l
تعداد نتایج: 25 فیلتر نتایج به سال:
Factor XIII on activation by thrombin cross-links fibrin. A common polymorphism Val to Leu at position 34 in the FXIII A subunit is under investigation as a risk determinant of thrombosis. Because Val34Leu is close to the thrombin cleavage site, the hypothesis that it would alter the function of FXIII was tested. Analysis of FXIII subunit proteolysis by thrombin using sodium dodecyl sulfate-pol...
BACKGROUND Although several studies in various countries have indicated that the presence of the E4 allele of the apolipoprotein-E (APOE) gene is a risk factor for ischemic cerebrovascular disease, the strength of this association still remains a matter of debate. OBJECTIVES The aim of the study was to determine the frequency of the APOE E4 allele and various other gene polymorphisms in in a ...
زمینه و هدف: تعدادی از پلی مورفیسمهای ارثی فاکتور های انعقادی با پاتوژنز ترومبوآمبولی وریدی و سایر پیامدهای جانبی آن ارتباط دارد. با توجه به اینکه اطّلاعات محدودی از فراونی این پلی مورفیسمها در جمعیّتهای ایرانی در دست است، لذا این مطالعه با هدف بررسی دو مورد از پلی مورفیسمهای فاکتور 13 یعنی XIIIA - V34L و XIIIB-H95R در جمعیّت سالم انجام شد. روش بررسی: در این مطالعه مقطعی 150 فرد سالم اهدا...
Cardiovascular diseases (CVDs) are significantly high in the Lebanese population with the two most predominant forms being atherosclerosis and venous thrombosis. The purpose of our study was to assess the association of a spectrum of CVD related genes and combined state of hypertension hypercholesterolemia (HH) in unrelated Lebanese. Twelve polymorphisms were studied by multiplex PCR and revers...
OBJECTIVE Fibrinogen is a target of autoimmune reactions in rheumatoid arthritis (RA). Fibrin(ogen) derivatives are involved in inflammatory processes and the generation of a stable fibrin network is necessary for sufficient inflammation control. As the density and stability of fibrin networks depend on complex interactions between factor XIIIA (F13A) and fibrinogen genotypes, the authors studi...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید