background: in recent years, dentists have more opportunity of treating patients infected with blood-borne pathogens. although compliance with infection control practice (icp) in dental practice is required, it is not still sufficiently spread in japan. objective: to identify factors associated with compliance with icps in the population of japanese dentists. methods: in a questionnaire-based c...

INTRODUCTION Melanosis coli is a benign lesion affecting the mucosa of the large intestine. There is a relationship between the presence of melanosis and anthraquinone laxative use. Melanosis coli is also observed in patients with colon cancer, but there is doubt whether these two conditions are related. AIM To analyze the correlation between melanosis and colon cancer. MATERIAL AND METHODS...

Pigmented contact dermatitis (PCD) is a noneczematous variant of contact dermatitis, characterized clinically by hyperpigmentation with little or no signs of dermatitis. The term “pigmented contact dermatitis” was coined by Osmundsen, a Danish dermatologist who described an epidemic of melanosis in Copenhagen.[1] In a series of excellent observations and investigations, he proved that the melan...

Primary acquired melanosis (PAM) is an acquired pigmentation of the conjunctival epithelium, a preinvasive pigmented lesion. When it is associated with cellular atypia it can lead to the developement of melanoma. We report a case report of malignant melanoma of the conjuntiva, which arrised from the conjuntival PAM. The disease was too extensive for ocular conservation, therefore exenteration w...

BACKGROUND To date, periorbital melanosis is an ill-defined entity. The condition has been stated to be darkening of the skin around the eyes, dark circles, infraorbital darkening and so on. AIMS This study was aimed at exploring the nature of pigmentation in periorbital melanosis. METHODS One hundred consecutive patients of periorbital melanosis were examined and investigated to define per...

Soft palatal melanosis can be detected by visual inspection during routine physical examination or even personally in a mirror. The aim of this study was to evaluate the association between squamous cell neoplasia in the upper aerodigestive tract (UAT) and soft palatal melanosis. We reviewed digitized records of high-quality endoscopic images of the soft palate of 1786 Japanese alcoholic men wh...

Two out of 60 conjunctival epithelial tumours reviewed between 1973 and 1989 were found to be pigmented. One tumour was a pigmented papilloma and the other a pigmented squamous cell carcinoma. The melanin pigment was found in epithelial tumour cells as well as in macrophages, dendritic melanocytes, and Langerhans cells. The distinction between the latter two types of cells was possible in one o...