I address and explain the increased risk of adverse effects from nutrients by using the paradigm of hormesis, the biological and toxicological concept that small quantities have opposite effects from large quantities. To provide necessary background, I categorize, depict, discuss, and contrast hormetic and other dose-response relations. I review some of the different hormetic mechanisms that ot...

Submit Manuscript | http://medcraveonline.com of nanostructures with the biological system of human being. Nanotoxicity occurs when biological system induces toxic biological responses due to the interaction with the properties of nanostructures either physical properties, chemical properties or both. Nanostructures include Nanoparticles, Nanotubes, Nanometals, Nanowire, Nanoballs and Nanocapsu...

Plastic materials are commonly used for storing food stuffs and medicines. Chemical substances used in the manufacture of plastic goods are found to migrate in the food stuffs used. The migration of UV absorbents and oxidisable matter was found to be more when used for longer periods.

The aim of this study was to see which harmful substances and which occupational settings most often required toxicological assessment, to evaluate exposure data provided by employers and to see to what extent could this assessment rely on actual measurements of harmful substances in a working environment. We reviewed the documentation that was submitted for toxicological assessment in all pati...

Background: Acute poisonings are common presentations to emergency departments (EDs) worldwide and require rapid assessment. Consultant emergency physicians (EPs) faced with various toxicological presentations must initiate rapid investigations and empirical management. This study aimed to determine emergency department doctors’ level of knowledge and confidence in toxicological presentations, ...

Many thousand organic compounds are in common use and new ones introduced daily. With many of these materials, little is known about their toxic hazard. For years scientists have been investigating the relation of structure and properties to biological activity. Among the factors relating to toxicity are bioaccumulation and persistence in the organism. In this study, the relation of partition c...

Experimental toxicological studies have offered clear evidence that benzene induces haematopoietic neoplasms, and it is generally accepted that exposure to benzene is a risk factor for leukaemia, in particular for acute non-lymphatic leukaemia. Quantitative aspects of benzene risk assessment are still a matter of controversy, however. In several risk assessments an estimated 50 deaths from leuk...