نتایج جستجو برای: toxicogenetics
تعداد نتایج: 24 فیلتر نتایج به سال:
Methyl-CpG-binding protein 2 (MeCP2) is generally considered to act as a transcriptional repressor, whereas recent studies suggest that MeCP2 is also involved in transcription activation. To gain insight into this dual function of MeCP2, we assessed the impact of MeCP2 on higher-order chromatin structure in living cells using mammalian cell systems harbouring a lactose operator and reporter gen...
Research Many elements and compounds present in the environment pose significant health risks to exposed individuals, and contribute to the burden of disease for society. For any exposed person the outcome may be affected by factors such as the degree of exposure, age, and genetically determined differences in uptake, elimination, or sensitivity to the toxic effects of the substance. Investigat...
Background: Tobacco use has toxic effects on different organs. This study was carried out to assess the effect of indigenous tobacco both in smoking (bidi) and smokeless (gutkha, zarda and khaini) forms on buccal cells at chromosomal level, through assessment of different nuclear anomalies as biomarker. Methods:This study was done on people living in Durgapur and its adjacent areas, West Bengal...
Genomics and Environmental Regulation is a canonical compilation of fundamental issues of this topic by leaders in the field. This timely work focuses on the potential and problems arising from the application of genomic technologies to toxicology and environmental policy, and is divided into four parts—“Environmental Policy Perspectives,” “Legal Perspectives,” “Occupational Health Perspectives...
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