Is visual input during critical periods of development crucial for the emergence of the fundamental topographical mapping of the visual cortex? And would this structure be retained throughout life-long blindness or would it fade as a result of plastic, use-based reorganization? We used functional connectivity magnetic resonance imaging based on intrinsic blood oxygen level-dependent fluctuation...

Is visual input during critical periods of development crucial for the emergence of the fundamental topographical mapping of the visual cortex? And would this structure be retained throughout life-long blindness or would it fade as a result of plastic, use-based reorganization? We used functional connectivity magnetic resonance imaging based on intrinsic blood oxygen level-dependent fluctuation...

Is visual input during critical periods of development crucial for the emergence of the fundamental topographical mapping of the visual cortex? And would this structure be retained throughout life-long blindness or would it fade as a result of plastic, use-based reorganization? We used functional connectivity magnetic resonance imaging based on intrinsic blood oxygen level-dependent fluctuation...

Calmodulin derivatives, specifically biotinylated in domains I and III, were synthesized to address the structures of calmodulin necessary for binding to its target enzymes in active conformations. By binding avidin to these biotinylated calmodulins, the role of specific sequences of the calmodulin molecule in target enzyme interactions could then be evaluated. The role of domain I in these int...

In many problems in science and engineering, it is often the case that there exist a number of computational models to simulate the problem at hand. These models are usually trade-offs between accuracy and computational expense. Given a limited computation budget, there is need to develop a framework for selecting between different models in a sensible fashion during the search. The method prop...

Electroencephalographic (EEG) and evoked activity can be recorded non-invasively in order to monitor human brain activation online. Electrical fields are generated by large intracranial neural populations and spread to the scalp through volume conduction. All measured signals depend on the location of the recording and reference electrodes. Simultaneous recordings from many scalp positions allo...

There is a topographical mapping of neural elements onto the lamina neuropile of the optic lobe of the cockroach, such that adjacent ommatidia project to adjacent points (optic cartridges) in the lamina neuropile. Postembryonic growth of the compound eye occurs by addition of new ommatidia to its growing margin. Retinula axons grow from the newly formed ommatidia to the lamina. By transplantati...

Self-Organizing Feature-Mapping (SOFM) algorithm is frequently used for visualization of high-dimensional (input) data in a lower-dimensional (target) space. This algorithm is based on adaptation of parameters in local neighborhoods and therefore does not lead to the best global visualization of the input space data clusters. SOFM is compared here with alternative methods of global visualizatio...