BACKGROUND Tephrosia purpurea is an Indian herb used in traditional medicine to treat various diseases such as jaundice, asthma, liver and urinary disorders. However, the anti-cancer potential of T. purpurea on hepatocellular carcinoma (HCC) is poorly understood. Therefore, this study aims to investigate the anti-cancer activity of T. purpurea in HepG2 hepatocellular carcinoma cells. METHODS ...

The ethanol extract of Tephrosia purpurea Linn. (Family: Leguminosae) was found to significantly inhibit the carbon tetrachloride-induced lipid peroxidation in vivo and superoxide generation in vivo. The ethyl acetate fraction of the same extract was studied for free radical scavenging and antilipid peroxidation activity. The IC 50 values in both of these in vitro assays were found to be signif...

Wild Indigo or Purple Tephrosia or fish poison occurs throughout the Indian subcontinent. It is widely used in the treatment of inflammation, diabetes, rheumatism, asthma, diarrhoea and many other ailments. But so far the pharmacognostic standardization has not been reported for its proper identification. Hence the present study is a pharmacognosy work carried out for the root part. This may he...

objective: martynia annua l. (m. annua), (martyniaccae) has been traditionally used in the treatment of epilepsy, sore throat and inflammatory disorders. the leaf paste is used topically on tuberculosis of the lymphatic glands and wounds of domestic animals. tephrosia purpurea (t. purpurea), (fabaceae) has been used traditionally as a remedy for asthma, gonorrhea, rheumatism and ulcers. this st...

The aim of the study was to evaluate the nephroprotective and nephrocurative effects of Tephrosia purpurea (L.) Pers. leaves against gentamicin-induced acute renal injury in albino rats. The maximum free radical scavenging activity of the ethanolic extract was the basis for the selection of this extract for the in vivo study. Gentamicin (40 mg/kg, s.c.) was administered to induce toxicity in th...

An attempt has been made to search for xanthine oxidase (XO) inhibitors from the root extracts of Tephrosia purpurea Linn. which is traditionally used in folk medicine in India. Root extracts were screened for in vitro antioxidant and xanthine oxidase inhibitory activity. Antioxidant activity was measured using ABTS, DPPH, FRAP and ORAC methods. The enzyme inhibitory activity was tested on puri...