This study was done for comparative evaluation of Hydrogel dressing with conventional dressing in 2nd degree burns involving up to 25 % of the total body surface area in our S.S.G. Hospital, Vadodara, Gujarat state, India from June 2005 to November 2006. In one group treatment with Hydrogel dressing was continued every three days and in the other group conventional dressing with Silver Sulfadia...

The present study deals with the formulation of ethosomal suspension containing silver sulfadiazine, followed by its incorporation into a hydrogel, leading to novel vesicular nano-ethogel sulfadiazine for treatment topical burns. Silver Sulfadiazine ethosomes were prepared hot method suggested Elka Touitou. This was loaded hydrogel made Carbopol 934 in ratio 1:1. chosen as gelling agent it do n...

result The combined search strategies led to the retrieval of 224 studies. After applying the eligibility criteria, based on titles and abstracts, 9 studies1-9 were selected for critical evaluation of texts. Of the studies, 8 were observational cohorts (7 historical and one prospective) and one systematic review. Patients included in the evidence were pregnant women with acute toxoplasmosis tre...

Cerebral toxoplasmosis is one of the most treatable opportunistic infections of the central nervous system in patients with the acquired immunodeficiency syndrome (AIDS).l,2 A combination of sulfadiazine and pyrimethamine is the therapy of choice, producing a favorable clinical response in 68 to 95 percent of patients receiving this regimen.3,4 Reports of sulfadiazine-induced crystalluria and r...

The in vitro and in vivo activities of catheters coated with minocycline and rifampin and with chlorhexidine gluconate and silver sulfadiazine were evaluated. When incubated in serum at 37 degrees C, the half-life of the inhibitory activity of catheters coated with minocycline and rifampin was 25 days compared with 3 days for catheters coated with chlorhexidine gluconate and silver sulfadiazine...

BACKGROUND Current guidelines recommend using antiseptic- or antibiotic-impregnated central venous catheters (CVCs) if, following a comprehensive strategy to prevent catheter-related blood stream infection (CR-BSI), infection rates remain above institutional goals based on benchmark values. The purpose of this study was to determine if chlorhexidine/silver sulfadiazine-impregnated CVCs could de...

This study aimed to investigate the effects of different doses of sulfadiazine on embryonic chicken pectoral muscles. In total, 100 fertile eggs were obtained and divided into five groups of control (no injection) and sulfadiazine injection at doses of 2, 10, 30, and 70 mg/kg. After hatching, pectoral muscle tissues were harvested from the newly hatched chickens for histopathological examinatio...

By H. G. PETERING, PH.D., R. A. DELOR, B.S., AND H. C. MURRAY, PH.D. F OLIC acid or vitamin B9 deficiency has been induced in the rat by feeding a purified diet containing succinyl sulfathiazole or sulfaguanidine)’2’3’4’5’6 This deficiency is corrected in either case by feeding free or conjugated pteroyl glutamic acid while the syndrome produced by sulfaguanidine is also corrected by paraaminob...

In the present study polyelectrolyte complexes (PECs) based on new sulfadiazine-chitosan conjugates with sodium hyaluronate have been developed with potential use in treatment of burn wounds. The PECs were chemically characterized using Fourier Transform-Infrared Spectroscopy, Scanning Electon Microscopy and Near Infrared Chemical Imaging Technique. The swelling behavior and in vitro sulfadiazi...

Several treatment failures have been reported for the treatment of toxoplasmic encephalitis, chorioretinitis, and congenital toxoplasmosis. Recently we found three Toxoplasma gondii strains naturally resistant to sulfadiazine and we developed in vitro two sulfadiazine resistant strains, RH-R(SDZ) and ME-49-R(SDZ), by gradual pressure. In Plasmodium, common mechanisms of drug resistance involve,...