Comparisons of recently published primary sequences of staphylococcal and streptococcal pyrogenic toxins prompted an evaluation of biological and immunological properties of the C terminus of staphylococcal enterotoxin C1. The 59 N-terminal amino acids were deleted from the toxin by digestion with trypsin. The resulting fragment (Mr, 20,659) contained the remaining 180 C-terminal residues. This...

The staphylococcal enterotoxins (SEs) are secreted by the bacteria Staphylococcus aureus and are the most common causative agent in staphylococcal food poisoning. The staphylococcal enterotoxin A (SEA) has been associated with large staphylococcal food poisoning outbreaks, but newer identified SEs, like staphylococcal enterotoxin H (SEH) has recently been shown to be present at similar levels a...

background : an accurate and prompt diagnosis of bacterial arthritis is essential for earlier treatment and a good outcome. superantigens produced by staph. aureus are among the most lethal toxins. the paper objective was identification of common bacterial antigens and s.aureus superantigens in synovial fluid (sf) of children with negative culture and direct smear for other bacteria except for ...

A third staphylococcal enterotoxin C (C3) has been identified, purified, and characterized. Staphylococcal enterotoxin C3 was identified from a Staphylococcus aureus isolated received from England. The purified toxin was determined by gel permeation chromatography and sodium dodecyl sulfate-polyacrylamide gel electrophoresis to be a simple protein with a molecular weight of 26,900. The isoelect...

Staphylococcal enterotoxin types A and C, were observed by viscosimetry and near-ultraviolet difference spectroscopy to unfold at concentrations of aqueous guanidine hydrochloride greater than 1 M. Apparent rate constants of unfolding calculated from spectral curves differed markedly for the two enterotoxins. Rate constants for the unfolding of enterotoxin A in 2 or 3 M guanidine hydrochloride ...

In this study, the enterotoxigenic potential of Staphylococcus strains (n = 574) isolated from raw milk samples (n = 140) was determined for their capacity to produce staphylococcal enterotoxins. In addition, the relationship between the presence of enterotoxins, coagulase, and thermonuclease (Tnase) was assessed. The results showed that 19% of Staphylococcus was enterotoxigenic, being able to ...

Background: T cell activation is discussed as an important factor in the pathogenesis of psoriasis. Recently, a lot of attention has been paid to the role of superantigens in T cell activation in the pathogenesis of psoriasis. In this study, the role of staphylococcal superantigens in the pathogenesis of psoriasis with identification of staphylococcal toxin levels in the skin lesions of p...

BACKGROUND Recent literature suggests that Staphylococcal enterotoxin specific IgE may be a risk factor for asthma. OBJECTIVE To investigate the associations between Staphylococcal enterotoxin sensitization and asthma. METHODS A systematic review and meta-analysis was performed for relevant case-control or population-based studies, published in the peer-reviewed journals until February 2013...

Staphylococcal enterotoxins (SEs) are powerful superantigens that stimulate non-specific T-cell proliferation produced by Staphylococcus aureus and draw considerable attention as ideal drugs for cancer therapy. The filtrate of S. aureus culture has been used as ampul named Staphylococcal enterotoxin C injection in clinic for 10 years in China and proved to be effective. The superantigen SEC cla...