Background: The balance between production of Reactive Oxygen Species (ROS) and antioxidant defense in the body has important health implications. The aim of this study was to investigate the changes in salivary antioxidants: catalase, vitamin C and brain-derived neurotrophic factor (BDNF), in sedentary men at rest and after acute exhaustive exercise.   Methods: This randomi...

background and aims. the antioxidant and anti-inflammatory properties of propolis were studied. since saliva contains antioxidants and radiotherapy of the head and neck mainly affects the saliva, salivary antioxidant defensive mechanism is compromised with oxidative stress produced by radiation therapy. therefore, the aim of the present study was to investigate the effect of propolis on salivar...

Background. We evaluated the concentrations of glutathione and uric acid, low molecular weight antioxidants, in saliva of patients with head and neck squamous cell carcinoma (HNSCC), in order to identify differences with normal subjects and to obtain information about biochemical alterations of human saliva during carcinogenesis. Methods. We compared 50 HNSCC patients, divided in 2 subsets on t...

background: the balance between production of reactive oxygen species (ros) and antioxidant defense in the body has important health implications. the aim of this study was to investigate the changes in salivary antioxidants: catalase, vitamin c and brain-derived neurotrophic factor (bdnf), in sedentary men at rest and after acute exhaustive exercise.   methods: this randomized controlled clini...

The use of saliva as a diagnostic fluid is a relatively recent trend. Saliva is a mixed oral fluid derived from major and minor salivary glands. Oral fluid, often called the mirror of the body’s health, is a perfect medium to be explored for health and disease surveillance. Saliva is considered to be the first line of defense against oxidative stress (OS), the main cause for many systemic and o...

background: oral cancer is among the 10 most common cancers worldwide with an increasing global incidence. compromised antioxidant defense system plays a role in occurrence of cancer. this study evaluated the salivary antioxidant level of oral cancer patients compared to a control group. patients and methods: this case-control study was conducted on 22 oral squamous cell carcinoma patients pres...

Oral lichen planus (OLP) is a chronic inflammatory mucosal disease of unknown etiology. Many studies have implicated the protective role of antioxidants in such diseases. The aim of this study was to compare salivary total antioxidant capacity (TAC and malondialdehyde (MDA) and antioxidant vitamin (vitamin s A, C and E) levels in patients with erosive OLP and healthy individuals. Thirty six pat...

Juvenile idiopathic arthritis (JIA) is the most common autoimmune inflammatory disease in children; joint inflammation is the hallmark of the disease. Thirty-five children with JIA were studied, of whom 26 had active disease and 14 were receiving anti-TNF therapy (5 with Infliximab, 9 with Etanercept). Sixteen healthy controls also were studied. Saliva samples were obtained for analysis of anti...

Cigarette smoke is injurious to both oral cavity and internal body environment. Saliva is the firstbody fluid to encounter the dangerous smoke. The aim of our present study was, therefore, toevaluate the influence of smoking on the antioxidant activity of saliva of healthy smokers.Antioxidant capacity of saliva was determined using different methods in the centrifuged saliva from25 male smokers...