OBJECTIVE This open-label study examined the effects of ramelteon on cognitive functions in 10 outpatients with schizophrenia. METHODS Ramelteon (8 mg/day) was administered to 10 patients with schizophrenia for six months. The verbal fluency test, Trail-Making Test, the Wisconsin Card Sorting Test, the Stroop Test, the Digit Span Distraction Test, Iowa Gambling Task, the Rey Auditory Verbal L...

BACKGROUND Few studies have simultaneously examined changes in physical, cognitive and emotional performance throughout the aging process. METHODS Baseline data from an ongoing experimental randomized study were analyzed. Physical activity, handgrip, the Senior Fitness Test, Trail Making Test A, Rey Auditory-Verbal Learning Test, Quality of Life-Alzheimer's Disease Scale (QoL-AD) and the Gold...

The purpose of the present study is to compare the effect of aging on direct and indirect measures of temporal order memory, derived from the Rey Auditory Verbal Learning Test (AVLT). The spontaneous order in which the list was recalled in Trial 5 served as the indirect measure, and the explicit reordering of the words into their original order of presentation (i.e., Trial 10) served as the dir...

Attention Deficit Hyperactivity Disorder (ADHD) is the most common neurobehavioural disorder of childhood. Although graphomotor deficits are not listed as a diagnostic criterion for ADHD, they are very common. It remains unclear, however, whether this is caused by motor deficits or by problems in planning and organizing behavior. The experimental group consisted of 30 boys with ADHD. The contro...

Mussel shells are potential bioarchives of proxies for changes in the physicochemical conditions in the bivalve’s habitat. One such proxy is the distribution of rare earths and yttrium (REY) in seawater, as REY speciation in seawater is sensitive to pH and temperature variations, due to the impact of these parameters on the activity of CO 3 in seawater. We present a new protocol for sample prep...

The consumption of a specifically prepared silk fibroin protein enzymatic hydrolysate (FPEH) has been reported to improve cognitive function in healthy humans. The objective of the current study is to evaluate the dose-dependent effects of the FPEH on memory. Healthy adults with an average age of approximately 55 years were administered doses of 0, 280, 400 and 600 mg of FPEH per day in two div...

AIM The purpose of this prospective study was to describe memory problems of adult patients with hydrocephalus. MATERIAL AND METHODS The research group consisted of healthy adults (control group) and hydrocephlic adults (hydrocephalus group). The hydrocephalus group (n: 19) had no clinical signs or symptoms of increased intracerebral pressure. The control group (n:20) was chosen from healthy ...

CONTEXT Neurofibromatosis type 1 (NF1) is among the most common genetic disorders that cause learning disabilities. Recently, it was shown that statin-mediated inhibition of 3-hydroxy-3-methylglutaryl coenzyme A reductase restores the cognitive deficits in an NF1 mouse model. OBJECTIVE To determine the effect of simvastatin on neuropsychological, neurophysiological, and neuroradiological outc...

OBJECTIVE To evaluate the efficacy and safety of soybean-derived phosphatidylserine (SB-PS) (300 mg/day) in improving cognitive performance in elderly with memory complaints, following a short duration of 12 weeks' SB-PS administration. METHODS SB-PS was administered daily for 12 weeks to 30 elderly volunteers with memory complaints (age range 50-90 years). Cognitive performance was determine...