BACKGROUND Although combination therapy consisting of 5-fluorouracil (5-FU) and cisplatin for the treatment of gastric cancer has been reported, no consistent regimen has been established. Our aim was to determine the optimal treatment schedule of this therapy, for patients with advanced or recurrent gastric cancer. PATIENTS AND METHODS We conducted a phase II study to evaluate the efficacy a...

background the number of patients with gastric cancer is growing worldwide. in iran (in 2009) of the 74067 new cases of cancer, 6886 were diagnosed as having gastric cancer. this study was conducted to investigate 5-year survival rate for gastric cancer in yazd province, central iran. methods in this descriptive study, the medical records of patients with gastric cancer were collected from the ...

background: combination chemotherapy is accepted as a high efficacy treatment for gastric cancer, whereas choice of standard treatment is unclear. multiple chemotherapeutic regimens have been used to achieve higher efficacy and lower toxicity. this study was designed to evaluate the treatment results of advanced gastric cancer with capecitabine and oxaliplatin regimen. subjects and methods : al...

The most effective treatment for gastric cancer is complete surgical resection with lymphadenectomy. However, a number of patients experience recurrence of the cancer even after curative surgery. This review focuses on comparative trials studying the use of adjuvant therapy with chemotherapy plus immunotherapy in the treatment of patients with curatively resected gastric cancer. Preoperative an...

abstract background: gastric cancer is one of the most common cancers in our country. recent studies have shown that adenocarcinoma of the cardia and distal stomach has increased in the past 25 years. however demographic data is lacking in this regard. methods: this study is a retrospective case series study. all records from 460 consecutive patients who were documented pathologically to have g...

Hereditary angioedema is a rare (1:50,000) hereditary chronic disease from the group of primary immunodeficiencies, which manifests in form recurrent skin and mucous membrane edema respiratory tract gastrointestinal tract. Pathogenesis this are associated with an increased risk number cardiovascular pathologies, complexity management choosing optimal treatment methods. This case report demonstr...

background: the incidence rate of esophageal squamouse cell cancer (escc) in eastern part of golestan province in iran is among the highest ones in the world. in order to discover the factors interplay in high rate of escc incidence, several case-control and cross-sectional studies were established in this area.as a cohort study has priority in detecting risk factors of a disease, a 10-year pro...

background gastric cancer is the second most common cause of cancer death worldwide. lentinan was shown to induce apoptosis in gastric cancer cells and could be used for the treatment of gastric cancer. objectives in this study, we analyzed anticancer effect of lentinan, a fungal β-glucan, on the gastric adenocarcinoma cell line (ags). materials and methods we used the dna ladder and tunnel app...

background: gastric cancer is the fifth most common cancer in the world and the third leading cause of death from cancer worldwide. this study aims to assess the epidemiology of gastric cancer in ardabil province, iran. methods: this was a descriptive cross-sectional study performed on 1056 patients with gastric cancer registered in the ardabil cancer registry. data were collected by a checklis...

A durable response after the discontinuation of immune checkpoint-inhibitor therapy has previously been reported in several cancers. We herein describe a patient with gastric cancer who maintained nivolumab. 65-year-old man was treated nivolumab as sixth-line for recurrent cancer. After four cycles therapy, he showed partial response. But treatment discontinued when two immune-related adverse e...