نتایج جستجو برای: recombinant human growth hormone

تعداد نتایج: 2440284  

Production and purification of human growth hormone using a simple method was studied in two recombinantEscherichia coli, D7-5 and C27-2 strains. The r-hGH was expressed in the form of inclusion body in a batchfermentation process and purified to 99% purity using a procedure based on acid precipitation of the hostderived proteins and other impurities. The effect of the pH and ...

ژورنال: دانشور پزشکی 2007
جورابچی, عصمت , حقیقی, هاله, قربانلی, مه لقا, هاشمی سهی, هاله,

Introduction: Human growth hormone (HGH) is very important pharmaceutical substance which is used as an absolute cure for different diseases that is why the production of HGH recombinant is taken into consideration not only nationally but also internationally. Many different methods and host systems have been used as growth hormone factories. Finding new and efficient hosts for recombinant mole...

Journal: :iranian journal of chemistry and chemical engineering (ijcce) 2010
ali akbar saboury safoura amiri

a binding study of nickel ions by a new recombinant human growth hormone (hgh), produced as an injected drug, has been done at 27˚c in nacl solution (50 mm) using an isothermal titration calorimetry. there is a set of three identical and non-interacting binding sites for nickel ions. the intrinsic dissociation equilibrium constant and the molar enthalpy of binding are 40 μm and -16.5 kj/mol, re...

Journal: :Clinical science 1992
F Salomon R C Cuneo R Hesp J F Morris L Poston P H Sönksen

1. The relationship of lean body mass, plasma insulin concentration and leucocyte active sodium transport with basal metabolic rate was investigated in 24 adults with growth hormone deficiency before and after treatment with recombinant human growth hormone and in 10 patients with untreated acromegaly. 2. Based on total-body potassium determined by whole-body 40K counting, patients with acromeg...

Journal: :The Journal of Clinical Endocrinology & Metabolism 2010

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