Three studies demonstrated that postsuppressional rebound (PSR) may be both reduced and enhanced by manipulating people's attributions about why they experience difficulty during suppression. Telling participants that suppression failures indicate a high motivation to use the suppressed construct produced more PSR than telling them that suppression failures indicate a low motivation to use the ...

The inhibitory output from the internal pallidum and substantia nigra to the thalamus forms an important link in the transmission of basal ganglia processing to cortex. Two hypotheses consider either inhibition of thalamic activity or thalamic excitation via post-inhibitory rebound burst firing as the functional mode of this link. We used optogenetics to characterize the synaptic properties of ...

BACKGROUND The evidence on the use of the oral dimethyl-fumarate after the discontinuation of treatment with natalizumab in people with Multiple Sclerosis is still little. Natalizumab discontinuation may induce the recurrence or rebound of the clinical and neuroradiological disease activity. Currently no therapeutic approach has been established to abolish disease reactivation and rebound after...

Parkinson's disease (PD) is a debilitating disorder resulting from loss of dopamine neurons. In dopamine deficient state, the basal ganglia increases inhibitory synaptic outputs to the thalamus. This increased inhibition by the basal ganglia output is known to reduce firing rate of thalamic neurons that relay motor signals to the motor cortex. This 'rate model' suggests that the reduced excitab...

The objective of this article is to report our experience on fingolimod suspension in multiple sclerosis patients. We evaluated clinical and magnetic resonance (MR) outcomes in six patients after fingolimod discontinuation. Within three months from fingolimod suspension, five subjects returned to pre-treatment disease activity; one patient, however, exhibited a clear rebound of clinical and MR ...

Our previous studies have demonstrated that inhaled nitric oxide (NO) decreases nitric oxide synthase (NOS) activity in vivo and that this inhibition is associated with rebound pulmonary hypertension upon acute withdrawal of inhaled NO. We have also demonstrated that inhaled NO elevates plasma endothelin-1 (ET-1) levels and that pretreatment with PD156707, an ETA receptor antagonist, blocks the...

1 Research Summary Comparing the security of single-SP and double-SP round functions on the generalized Feistel. – Assumption: an infinite number of rounds – Results: double-SP causes more active S-boxes than single-SP, and thus double-SP is more secure. – Motivation: a number of rounds is small in practice. – Results: For 6 or 7 rounds, the rebound attack works more for double-SP than single-SP.

3 in particular alpha activity in this context has not yet been studied. In a second study, patients with liver cirrhosis and varying degrees of HE and healthy control subjects received electrical stimulation of sensory fibers of the right median nerve. The stimulus-induced rebound of alpha activity within the primary somatosensory cortex (S1) contralateral to the stimulated hand significantly ...

In vivo, neurons of the globus pallidus (GP) and subthalamic nucleus (STN) resonate independently around 70 Hz. However, on the loss of dopamine as in Parkinson's disease, there is a switch to a lower frequency of firing with increased bursting and synchronization of activity. In vitro, type A neurons of the GP, identified by the presence of I(h) and rebound depolarizations, fire at frequencies...