BACKGROUND A prolonged QTc interval on electrocardiography is often used as a surrogate marker for ventricular arrhythmia. Medications that can prolong the QTc interval may increase the risk of cardiac complications, although the exact incidence is unknown. It is reasonable to assume that administration of QTc-prolonging medications to patients with pre-existing QTc prolongation will further in...

provided the original work is properly cited. CC Min et al. [1] investigated the effects of palonosetron, a second-generation 5-hydroxytryptamine-3 receptor antagonist, on corrected QT (QTc) intervals on electrocardiograms of patients undergoing laparotomies under sevoflurane anesthesia. Considering that prolongation of the QTc interval is associated with torsades de pointes, and palonosetron m...

OBJECTIVES We evaluated the incremental prognostic information provided by multiple corrected QT (QTc) measurements on serial electrocardiograms (ECGs) in patients with the inherited long QT syndrome (LQTS). BACKGROUND A baseline QTc of > or =500 ms has been shown to be associated with increased risk of cardiac events among LQTS patients. However, the value of QTc measurements on follow-up EC...

A model to predict risk of mortality may be useful guide treatment decisions for patients at prolonged QTc. This study aimed evaluate the relationship between a modified Tisdale QTc interval score (QTc-RS) and inpatient mortality. was retrospective observational study. QTc-RS calculated across 30 hospitals in U.S. The ranges from zero 23 incorporates following factors: sex, age>67 years, loop d...

AIM To assess the relationship between corrected QT (QTc) interval and vitamin 25-hydroxyvitamin D levels (25-OHD) deficiency in type 2 diabetic patients. METHODS The study included 253 patients with type 2 diabetes and 170 age-matched controls treated between October and December 2013. QTc duration and QTc dispersion were measured on ECG recordings and 25-OHD, calcium, phosphorus, and blood ...

OBJECTIVE To analyze the effect of age on the ECG QT interval, an important predictor of cardiovascular mortality and drug-induced cardiac arrhythmias, and determine whether QT-heart rate correction formulae (QTc) have differential relationships with age and sex. METHODS Data were examined from the US National Health and Nutrition Examination Survey (NHANES) II and III, civilian population ag...

OBJECTIVE To determine whether hyperglycaemia is associated with prolongation of the corrected QT (QTc) interval on the electrocardiogram (ECG) in critically ill patients. DESIGN Single-centre, prospective observational study. PARTICIPANTS AND SETTING 197 consecutive patients admitted to the adult intensive care unit of a 570-bed teaching hospital over 10 weeks from November 2004. MAIN OU...

background: prolongation of qt interval is one of the most important abnormalities in cardiovascular system of cirrhotic patients. the aim of this survey was determination of propranolol effect on frequency adjusted qt interval (qtc). materials and methods: thirty six cirrhotic patients (m/f=20/16, mean age:56 â± 3.8 years) and 40 healthy age and sex matched controls (m/f=25/15, mean age: 58 â±...