The effect of a single and multiple doses of polyinosinic-polycytidylic acid (poly (I). poly(C) on lactic dehydrogenase virus viremia has been studied. A single injection of 200 mug of poly (I)-poly(C) given 6 h before infection with lactic dehydrogenase virus caused a temporary decrease in viremia of about 2.5 log10. Repeated injections of 100 mug of poly(I)-poly(C) every 24 h beginning at -24...

in this study, porous scaffolds from poly(d,l-lactic acid) have been prepared via liquid- liquid phase separation method in ternary system of polymer-1,4-dioxane-water. polymer dissolved in dioxane in 1.5, 2.5 and 5 % wt/v and the solvent/non-solvent ratios were 13/87, 15/85 and 17/83. cloud point curves prepared by visual turbidometry. in order to obtain porous scaffolds with inter-connected p...

lysozyme, as a model protein, was precipitated through the formation of protein-zn complex to micronize for subsequent encapsulation within poly (lactic-co-glycolic acid) (plga) microspheres. various parameters, including ph, type and concentration of added salts and protein concentration, were modified to optimize the yield of protein complexation and precipitation. the resulting protein parti...

The ability of some microorganisms to use lactic acid stereocopolymers and copolymers with glycolic acid as sole carbon and energy sources was studied under controlled or natural conditions. First, 14 filamentous fungal strains were tested in liquid cultures, adopting total lactic acid consumption, nitrogen source exhaustion, and maximal biomass production as selection criteria. Two strains of ...

As people in the 21st century become increasingly environmentally aware, environmentally friendly products have come into focus. As such, environmentally friendly textiles and eco-textiles have become an international trend in research and development. Poly(lactic acid) fiber, which is biodegradable, holds much promise, but it is difficult to deep dye. This study used chitosan, succine anhydrid...

Tissue engineering is a rapidly advancing technology in the field of regenerative medicine. For the transplantation of cell sheets, a carrier must maintain the shape of a cell sheet from a culture dish to affected sites as well as release the sheet easily onto the lesion. In this study, we examined the utility of a novel, poly(lactic acid)-based carrier for cell sheets transplantation to the co...