In recent years, the anti-tumor effect of panax notoginseng saponins (PNS) has been widely acknowledged by multiple in vivo and in vitro experiments. However, few studies have focused on the effect of PNS on chronic myeloid leukemia cells. In this study, we mainly explored the effect of PNS on K562 cell apoptosis and autophagy, thereby exploring its potential application in the treatment of chr...

A sample of 27 Planetary Nebulae (PNs) in the Small Magellanic Clouds (SMC) have been observed with the Hubble Space Telescope Imaging Spectrograph (HST/STIS) to determine their morphology, size, and the spatial variation of the ratios of bright emission lines. The morphologies of SMC PNs are similar to those of LMC and Galactic PNs. However, only a third of the resolved SMC PNs are asymmetric,...

Petri Nets (PNs) and their variations are a graphical, mathematical language that can be used for the specification, analysis and verification of discrete event systems, including Critical Infrastructures (CIs). Colored PNs are an extension of classical PNs that are suitable for modeling and analyzing complex interconnected CIs. Timed PNs are another extension of PNs that support timing constra...

The mammalian cerebral cortex is typically organized in six layers containing multiple types of neurons, with pyramidal neurons (PNs) being the most abundant. PNs in different cortical layers have distinct morphology, physiology and functional roles in neural circuits. Therefore, their development and synaptic plasticity may also differ. Using in vivo transcranial two-photon microscopy, we foll...

The diagnosis of a paraneoplastic syndrome (PNS) may precede, follow or be concurrent with the diagnosis of a malignant tumor. There is increasing knowledge of association between PNS and head and neck cancers, but the relationship between oral cancer and paraneoplastic disease has not been previously investigated. PNS associated with head and neck cancer can be divided into six main groups: en...

BACKGROUND The gender-specific influences of various confounding factors, including apnea, age, BMI, and cigarette consumption, on the function of the parasympathetic nerve system (PNS) during sleep in OSA patients has never been investigated. METHODS One hundred ninety-seven males and 63 females with OSA were subjected to full PSG examinations including assessment of R-R intervals (RRIs) dur...

Proof-Number Search (PNS) is a powerful method for solving games and game positions. Over the years, the research on PNS has steadily produced new insights and techniques. With multi-core processors becoming established in the recent past, the question of parallelizing PNS has gained new urgency. This article presents a new technique called Randomized Parallel Proof-Number Search (RP–PNS) for p...

OBJECTIVE To investigate any association between renal cell carcinoma (RCC) and paraneoplastic syndromes (PNS). SUBJECTS AND METHODS The retrospective analysis included 1,028 patients of Chinese Han nationality with resectable RCC and PNS. The PNS included elevated erythrocyte sedimentation rate (ESR), hypertension, cachexia, anemia, pyrexia, abnormal liver function, hypercalcemia, polycythem...

Personal need for structure (PNS) refers to individual differences in tendency to structure huge amounts of information into a simplified form, and was frequently examined in previous research in association with strategies for reducing cognitive load and with creativity. The present research developed a new Japanese-translated version of the PNS Scale (PNS-J) and conducted two surveys with sam...