Small-angle x-ray scattering was used to investigate structural changes upon binding of individual substrates or a transition state analog complex (TSAC; Mg-ADP, creatine, and KNO3) to creatine kinase (CK) isoenzymes (dimeric muscle-type (M)-CK and octameric mitochondrial (Mi)-CK) and monomeric arginine kinase (AK). Considerable changes in the shape and the size of the molecules occurred upon b...

Nimodipine and its solvent containing ethanol were tested in a randomized in vivo study by local administration to the outer vessel wall surface of pial arteries and veins in 15 anesthetized cats. Reactions were studied through a cranial window. Diameter variations of 90 arterial and 78 venous vessel segments were continuously analyzed using a multichannel videoangiometer. The solvent alone cau...

Six crossbred steers (261 +/- 18 kg BW) fitted with hepatic portal, mesenteric venous and arterial catheters, and duodenal, midjejunal, and ileal cannulas were used in a replicated 3 x 3 Latin square design to determine the effect of varying levels and site of glucose plus 2-deoxyglucose (2DG) infusion on net portal-drained visceral flux. Steers were fed chopped alfalfa in six equal portions da...

child safety seat mishandle is still a concern. to prevent serious injuries and death from automotive accidents, correct use of car seats for small children is essential. failure to use a car seat properly can contribute to serious injury or death of a child. recent studies have shown that child safety seats can tolerate the impact of a minor crash without affecting their future performance. fa...

Objective: Few non-surgical conditions are more painful than rib fractures. There are a few methods for pain relief in patients with minor rib fractures. Methods: We used a non-steroidal anti-inflammatory drug (NSAID, Naproxen sodium) and transcutaneous electrical nerve stimulator (TENS) to control pain of the patients with uncomplicated minor rib fractures. One hundred consecutive patients adm...

Growth studies with Lemna minor revealed the additive and synergistic growth-inhibiting properties of the canaline-urea cycle amino acids. Simultaneous canavanine and canaline treatment caused an additive reduction in frond production. Ureidohomoserine interacted with canaline or canavanine to affect synergistically L. minor growth by enhancing individual canavanine or canaline toxicity and inc...

We derive precise asymptotic estimates for the number of labelled graphs not containing K3,3 as a minor, and also for those which are edge maximal. Additionally, we establish limit laws for parameters in random K3,3-minor-free graphs, like the expected number of edges. To establish these results, we translate a decomposition for the corresponding graph class into equations for generating functi...

We derive precise asymptotic estimates for the number of labelled graphs not containing K3,3 as a minor, and also for those which are edge maximal. Additionally, we establish limit laws for parameters in random K3,3-minor-free graphs, like the number of edges. To establish these results, we translate a decomposition for the corresponding graphs into equations for generating functions and use si...

Alpha-thalassemias are characterized by decreased hemoglobin alpha chain synthesis; alpha-zerothalassemia being the condition where no normal alpha globin is produced, and alpha-plus-thalassemia being the condition where there is reduced globin production. There are two alpha globin genes per haploid genome, and alpha thalassemia abnormalities can result from one to four gene deletions. A singl...

Alpha-thalassemias are characterized by decreased hemoglobin alpha chain synthesis; alpha-zerothalassemia being the condition where no normal alpha globin is produced, and alpha-plus-thalassemia being the condition where there is reduced globin production. There are two alpha globin genes per haploid genome, and alpha thalassemia abnormalities can result from one to four gene deletions. A singl...