The formulation of natural substances together with a biocompatible or biodegradable carrier material to form composites or encapsulates has a great relevance for pharmaceutical, cosmetic and food industries. The main objective of this article is taking a look at microencapsulation as a novel drug delivery system. Its scope extends beyond conventional microcapsules to all other small particulat...

in this study, simple, fast and reliable cyclic voltammetry (cv), linear sweep voltammetry (lsv), square wave voltammetry (swv) and differential pulse voltammetry (dpv) methods were developed and validated for determination of bosentan in pharmaceutical preparations. the proposed methods were based on electrochemical oxidation of bosentan at platinum electrode in acetonitrile solution containin...

OBJECTIVE To assess the effectiveness of a product-analysis laboratory exercise in teaching students the importance of quality in pharmaceutical compounding. DESIGN Second-year pharmacy students (N=77) participated in a pharmaceutical compounding laboratory exercise and subsequently analyzed their final product using ultraviolet (UV) spectrometry. ASSESSMENT Reflection, survey instruments, ...

medicines and of the methods of preparing and prescribing them, with a sketch of their action, physiological and therapeutic. There is a chapter on weights, measures, and pharmaceutical apparatus, another on the sources, selection and adulteration of drugs, including their active principles. The operations of pharmacy, crystallizing, decocting, digesting, distilling, &c., are fully and practica...

Efficiency is one of the most important criteria in departments responsible for the production of compounds in a library format. Consequently, this was a key factor in the initial design of our automated medicinal chemistry department, established some years ago. Nonetheless, we were able to improve and optimize our workflows and processes constantly. Here, we outline our current setup, from de...

Cocrystals can be used as an alternative approach based on crystal engineering to enhance specific physicochemical and biopharmaceutical properties of active pharmaceutical ingredients (APIs) when the approaches to salt or polymorph formation do not meet the expected targets. In this article, an overview of pharmaceutical cocrystals will be presented, with an emphasis on the intermolecular inte...