opium is a derivative of opium poppy; the species of plant which its extract is used for preparing opium. opium abuse is considered under drug dependency classification of psychiatric diseases and opium abusers have a number of major challenges before, during and after anesthesia for surgical operations (i.e. the perioperative period). this article reviews these clinical challenges during the p...

The rapid detection and evaluation of patients presenting with perioperative neurological dysfunction is of great clinical relevance. Biomarkers have been defined as biological molecules that can be used as an indicator of new onset or progression of a biological process or effect of treatment. Biomarkers have become increasingly important in this setting to supplement other modalities of diagn...

Hyperglycemia is a common finding in surgical patients during the perioperative period. Factors contributing to poor glycemic control include counterregulatory hormones, hepatic insulin resistance, decreased insulin-stimulated glucose uptake, use of dextrose-containing intravenous fluids, and enteral and parenteral nutrition. Hyperglycemia in the perioperative period is associated with increase...

• Understand the mechanisms behind the metabolic effects of trauma; • How does the stress response after traumatic injury lead to hypermetabolism; • What does this mean for protein metabolism; • Can certain aspects of the stress response after acute non-surgical trauma be avoided and how can they be treated; • Insights into the relationship between hypermetabolism, alterations in protein metabo...