background periodontium may be able to respond to injuries by regeneration via the function of stem cells. objectives this study sought to assess the differentiation of human periodontal ligament stem cells (pdlscs) into osteoblasts in standard osteogenic medium and in a medium supplemented with 1,25-dihydroxyvitamin d3 (calcitriol). materials and methods in this experimental study, pdlscs were...

The periodontal ligament lies between the hard tissues of alveolar bone and cementum of teeth and serves to anchor the tooth to the alveolus and functions as a cushion between these hard tissues to migrate occlusal force during mastication. This tissue is always exposed to mechanical stress during mastication. When occlusal forces exceed the adaptive capacity of the periodontal ligament, the pe...

objectives: periodontal tissue regeneration for treatment of periodontal disease has not yet been mastered in tissue engineering. stem cells, scaffold, and growth factors are the three main basic components of tissue engineering. periodontal ligament (pdl) contains stem cells; however, the number, potency and features of these cells have not yet been understood. this study aimed to isolate and ...

there is evidence indicating that pomegranate juice contains many of the essential properties necessary to retain cell viability and cell proliferation. these properties indicate that pomegranate juice is a suitable storage medium for avulsed teeth. however, this idea has not yet been tested. in this study, the capacity of pomegranate juice (pj) as a storage medium for retaining avulsed teeth w...

INTRODUCTION Auto-transplantation of third molars is frequently undertaken in order to restore a perfect occlusion and to improve mastication following a substantial loss of molars. However, little is known about the precise role of the periodontal membrane during this procedure. Therefore, we investigated if the epithelial rests of Malassez persist in the periodontal ligament of auto-transplan...

Objective: To develop and validate a three-dimensional (3D) numerical model of a maxillary central incisor to simulate tooth movement using the Finite Element Method (FEM). Methods: This model encompasses the tooth, alveolar bone and periodontal ligament. It allows the simulation of different tooth movements and the establishment of centers of rotation and resistance. It limits the movement int...

Idiopathic root resorption is a very rare phenomenon. Resorption in tooth is brought about by odontoclastic activity. Special mechanisms in the periodontal ligament exist to prevent mineralization of the periodontal ligament and these periodontal ligament cells produce factors that inhibit mineralized tissue resorption and are capable of regulating bone and cementum formation. When this mechani...

Orthodontic force-induced stresses cause dynamic alterations within the extracellular matrix and within the cytoskeleton of cells in the periodontal ligament and alveolar bone, mediating bone remodelling, ultimately enabling orthodontic tooth movement. In the periodontal ligament and alveolar bone, the mechanically induced tensile strains upregulate the expression of osteogenic genes resulting ...

objectives: this study was undertaken to evaluate the viability of periodontal ligament (pdl) cells of avulsed teeth in three different storage media. materials and methods: forty-five premolars extracted for orthodontic therapeutic purposes were randomly and equally divided into three groups based on storage media used [group i: milk (control); group ii: aloe vera (experimental); group iii: eg...