Background: Intraoperative radiation therapy (IORT) technique is used to treat a surgically exposed tumor or tumor bed in the treatment of locally advanced intraabdominal, retroperitoneal, pelvic, thoracic, breast and soft tissue tumors. One way to perform IORT is to use an existing linac and modify the treatment head using an applicator system. In this study the objectives were to design, and ...

geant4 is an open source simulation toolkit based on c++, which its advantages progressively lead to applications in research domains especially modeling the biological effects of ionizing radiation at the sub-cellular scale. however, it was shown that geant4 does not give a reasonable result in the prediction of antiproton dose especially in bragg peak. one of the reasons could be lack of a re...

background: intraoperative radiation therapy (iort) technique is used to treat a surgically exposed tumor or tumor bed in the treatment of locally advanced intraabdominal, retroperitoneal, pelvic, thoracic, breast and soft tissue tumors. one way to perform iort is to use an existing linac and modify the treatment head using an applicator system. in this study the objectives were to design, and ...

PURPOSE To compare the sensitivity of flatness based energy metrics versus an attenuation based metric (percent depth dose) as a function of energy changes from the linac's nominal clinical energy. METHODS Energy changes were accomplished by adjusting the bending magnet current (BMI) ±15% away from the value used clinically. Two metrics for flatness, relative flatness in the central 80% of th...

This study aims to determine the average absorbed dose of radiation in glandular tissue during mammography and to investigate factors that influence the average glandular dose, particularly the local distribution of glandular tissue within the breast and breast skin thickness. An EGSnrc Monte Carlo code and associated codes were employed in the simulation. The breast voxel models used consist o...

background: radiation-sensitive polymer gels are among the most promising three-dimensional dose verification tools and tissue-like phantom developed to date. objective: the aim of this study is an investigating of percentage depth dose enhancement within the gel medium with used of conformal distribution gold nanoparticle as contrast agents by high atomic number material. methods: in this work...

PURPOSE Describe the Radiological Physics Center's (RPC) extensive standard dosimetry data set determined from on-site audits measurements. METHOD AND MATERIALS Measurements were made during on-site audits to institutions participating in NCI funded cooperative clinical trials for 44 years using a 0.6cc cylindrical ionization chamber placed within the RPC's water tank. Measurements were made ...

During implementation of the total skin electron treatment, using six-dual-field technique, at radiotherapy department a large number of measurements are needed. To assess depth dose curve required by clinicians and dose uniformity over a whole treatment plane, combinations of different irradiation parameters are used (electron energy, beam angle, scatterers). Measurements for each combination ...

This study details the generation, verification, and implementation of a treatment planning system (TPS) couch top model for patient support system used in conjunction with a dedicated stereotactic linear accelerator. Couch top model was created within the TPS using CT simulation images of the kVue Calpyso-compatible couchtop (with rails). Verification measurements were compared to TPS dose pre...