Peptic ulcer disease (PUD) is considered as one of the common diseases in the world. Treatment of peptic ulcer with synthetic drugs such as proton pump inhibitors, H2 receptor antagonists and other non-steroidal anti-inflammatory drugs has shown adverse effects, relapses, drug interactions. Medicinal plants containing active chemical constituents are useful in prevention and treatment of variou...

Measurements were made of the amounts of histamine extracted from patients with peptic ulcer disease and control subjects suffering from various gastrointestinal diseases. Patients with duodenal ulcer, gastric ulcer, or recurrent duodenal ulcer after proximal gastric vagotomy often had less gastric mucosal histamine than did normal controls. Cimetidine therapy increased the amounts of the hista...

Acid peptic diseases are common gastrointestinal disorders, which include gastroesophageal reflux disease, peptic ulcers, non-ulcer dyspepsia and stressrelated gastric mucosal injury. Drugs commonly used in the management of these disorders include antacids, H2 blockers, proton pump inhibitors and mucosal protective agents. In this chapter, pharmacology of these drugs will be discussed, followe...

Acid peptic diseases are common gastrointestinal disorders, which include gastroesophageal reflux disease, peptic ulcers, non-ulcer dyspepsia and stressrelated gastric mucosal injury. Drugs commonly used in the management of these disorders include antacids, H2 blockers, proton pump inhibitors and mucosal protective agents. In this chapter, pharmacology of these drugs will be discussed, followe...

Acid peptic diseases are common gastrointestinal disorders, which include gastroesophageal reflux disease, peptic ulcers, non-ulcer dyspepsia and stressrelated gastric mucosal injury. Drugs commonly used in the management of these disorders include antacids, H2 blockers, proton pump inhibitors and mucosal protective agents. In this chapter, pharmacology of these drugs will be discussed, followe...

Identification of the pathogenic role of H. pylori in fection has revolutionized the approach toward chronic gastritis, peptic ulcer disease, gastric MALT (mucosa associated lymphoid tissue) lymphoma and gastric can cer. These diseases often result from infection of H. pylori, the accompanying host inflammatory response and the interaction with environmental factors. Eradi cation treatment agai...

Background. Interventional endoscopy has largely reduced mortality in patients with peptic ulcer hemorrhage. Study aims. To evaluate the efficacy and safety of endoscopic hemostasis with argon plasma coagulation and injection sclerotherapy in bleeding peptic ulcer and determine the mortality of patients in a prospective, controlled study. Patients and methods. The study includes 100 patients wi...

Double pylorus is an unusual condition in which a double communication between the gastric antrum and the duodenal bulb occurs. It may be congenital, or it may be acquired complication of peptic ulcer disease. We present a case of double pylorus in a gentleman with epigastric pain and previous history of peptic ulcer disease. The relationship between Helicobacter pylori and this disease was ass...

The present study aimed to investigate the association between endothelial progenitor cells (EPCs) and peptic ulcers in patients with or without type 2 diabetes mellitus (T2DM), in association with the efficiency of peptic ulcer treatment. The study recruited healthy subjects and peptic ulcer patients with or without T2DM. All the ulcer patients, including those with and without T2DM, were admi...