نتایج جستجو برای: osteoinduction

تعداد نتایج: 266  

2017
Michail E. Klontzas Spyros I. Vernardis Manolis Heliotis Eleftherios Tsiridis Athanasios Mantalaris

Mesenchymal stem cells (MSCs) of fetal origin, such as umbilical cord blood MSCs (UCB MSCs), have emerged as a promising cell source for musculoskeletal tissue regeneration because of their higher proliferation potential, lack of donor site morbidity, and their off-the-shelf potential. MSCs differentiated toward the osteogenic lineage exhibit a specific metabolic phenotype characterized by reli...

2017
Fei Yang Chen Chen QianRong Zhou YiMing Gong RuiXue Li ChiChi Li Florian Klämpfl Sebastian Freund XingWen Wu Yang Sun Xiang Li Michael Schmidt Duan Ma YouCheng Yu

Fabricating Ti alloy based dental implants with defined porous scaffold structure is a promising strategy for improving the osteoinduction of implants. In this study, we use Laser Beam Melting (LBM) 3D printing technique to fabricate porous Ti6Al4V dental implant prototypes with three controlled pore sizes (200, 350 and 500 μm). The mechanical stress distribution in the surrounding bone tissue ...

Journal: :Einstein 2011
Igor Iuco Castro-Silva Letícia de Oliveira Castro Janaína José Dos Santos Machado Maria Helena Alves Nicola José Mauro Granjeiro

OBJECTIVE The aim of this study was to evaluate the osteogenic potential of human umbilical cord blood-derived osteoprogenitor cells and to prove its applicability as a promising candidate for cell-based therapeutics for bone repair. METHODS Primary cultures of human umbilical blood cord adherent cells were expanded in vitro until passage 2 and seeded for osteodifferentiation study. Morpholog...

Journal: :Circulation research 2013
Yucheng Yao Medet Jumabay Albert Ly Melina Radparvar Mark R Cubberly Kristina I Boström

RATIONALE Vascular calcification is a regulated process that involves osteoprogenitor cells and frequently complicates common vascular disease, such as atherosclerosis and diabetic vasculopathy. However, it is not clear whether the vascular endothelium has a role in contributing osteoprogenitor cells to the calcific lesions. OBJECTIVE To determine whether the vascular endothelium contributes ...

2017
Kyung-Jung Kang Min Suk Lee Chan-Woong Moon Jae-Hoon Lee Hee Seok Yang Young-Joo Jang

Human dental pulp cells have been known to have the stem cell features such as self-renewal and multipotency. These cells are differentiated into hard tissue by addition of proper cytokines and biomaterials. Hydroxyapatite-tricalcium phosphates (HA-TCPs) are essential components of hard tissue and generally used as a biocompatible material in tissue engineering of bone. Demineralized dentin mat...

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