OBJECTIVE To evaluate some epidemiologic and aetiologic factors for male infertility in our patients. METHOD All male patients who presented with infertility in urology clinic of the department of surgery between 1991and2005 were retrospectively reviewed. Epidemiologic and aetiological factors of male infertility were studied. RESULT There were 537 patients; age ranged 18 to 56 years with a...

INTRODUCTION Although assisted reproduction techniques are used extensively in Iran, screening for Y chromosome microdeletions before intracytoplasmic sperm injection is often undervalued. Our aim was to investigate Y chromosome microdeletions in men with idiopathic azoospermia or severe oligospermia. MATERIALS AND METHODS In 99 selected patients with azoospermia or severe oligospermia and el...

The non-recombining portion of the Y-chromosome contains numerous polymorphisms; therefore, it is now the most informative haplotyping system with wide-ranging applications. Idiopathic azoospermia and oligospermia are among the most important causes of male infertility. Different haplogroups may have different genetic backgrounds, which may be either susceptible or unsusceptible to idiopa...

OBJECTIVE To investigate the effect of chemotherapy on gonadal function of young men cured of childhood Hodgkin's disease. METHODS Young adult males surviving Hodgkin's disease, aged 17 and over at least 2 years after therapy were studied in Ali Asghar Children's Hospital, Tehran, Iran from March 2000 to March 2005. Clinical evaluation for secondary sexual characteristics, semen analysis, fol...

The range of variability in the population distribution characteristics of sperm DNA content was surveyed in a selected group of donors. The donors included identical twins, carriers of chromosomal translocations, and oligospermics. The DNA content of sperm was measured individually in an automated cytofluorometer. In contrast to normal donors with high sperm counts and relatively constant moda...

The outcomes of drug treatment for male infertility remain conjectural, with controversial study results. Our pilot study employed a randomized, placebo-controlled, crossover methodology with intention-to-treat analysis. Thirty-three men with idiopathic oligospermia were randomized to start either daily oral lisinopril 2.5 mg (n = 17) or daily oral placebo (n = 16). Lisinopril was found to caus...

Objective: Microdeletions of azoospermia factor (AZF) regions in Y chromosome were a genetic risk factor of spermatogenic failure and male infertility. Most laboratories carried out the AZF microdeletion testing by using peripheral intravenous blood, and AZF microdeletion in spermatozoa of infertile patients was sometimes not identical to that of peripheral intravenous blood due to the existenc...

OBJECTIVE To determine the prevalence of low sperm count including oligospermia and azoospermia in male infertile population, and to assess the pattern and distribution of abnormal semen parameters in infertile men. METHODS The descriptive cross-sectional survey was carried out at the Department of Gynaecology and Obstetrics, Sharif Medical City Hospital, Lahore, from June 2009 to June 2010. ...

BACKGROUND Several studies suggest a decrease in sperm quality in men in the last decades. Therefore, the aim of this work was to assess the influence of male factors (sperm quality and paternal age) on the outcomes of conventional in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI). METHODS This retrospective study included all couples who underwent IVF or ICSI at Montpe...