introduction: laryngopharyngeal reflux (lpr) is considered an important cause of voice disorder. we aimed to determine the frequency of lpr in patients with voice disorder and the association between koufman reflux symptom index (rsi), reflux finding score (rfs), gastroesophageal reflux disease (gerd), and proximal acid reflux in these patients. materials and methods: we performed a prospective...

background: gastroesophageal reflux disease (gerd) is one of the most common gastrointestinal problems in the west while different reports indicate an increase in the prevalence in iran. the aim of this study was to estimate the preva­lence and clinical spectrum of gerd in staff of a referral hospital and evaluate the risk factors. methods: this cross-sectional study using a modified mayo clini...

UNLABELLED BACKGROUND Gastroesophageal reflux disease (GERD) is a common cause of chronic cough. Both acid and nonacid reflux is thought to play a role in the initiation of coughing and cough hypersensitivity. The GABAB receptor agonist lesogaberan was developed as a peripherally restricted anti-reflux therapy that reduces the frequency of transient lower esophageal sphincter relaxations (TL...

OBJECTIVES Children with severe cerebral palsy (CP) commonly have gastrointestinal (GI) dysfunction. Whey-based enteral formulas have been postulated to reduce gastroesophageal reflux (GOR) and accelerate gastric emptying (GE). The authors investigated whether whey-based (vs casein-based) enteral formulas reduce GOR and accelerate GE in children who have severe CP with a gastrostomy and fundopl...

BACKGROUND Nocturnal acid reflux is associated with symptomatic and asymptomatic sleep arousals, leading to fragmented sleep. The frequency and influence of acid reflux in patients with various forms of insomnia has not been reported. The aim of this study was to quantify nocturnal acid and nonacid reflux in patients with primary sleep disorders as previously diagnosed by polysomnography. MET...

Background Esophageal multichannel intraluminal impedance-pH monitoring has become one of the preferred tests to correlate observed reflux-like behaviors with esophageal reflux events. The Gastroesophageal reflux disease Assessment Symptom Questionnaire is a validated tool used to distinguish infants with gastroesophageal reflux disease from healthy children. The aim of this study was to determ...

BACKGROUND People with proven gastroesophageal reflux disease may also experience symptoms such as voice loss, chronic cough, globus, and sore throat. These laryngopharyngeal reflux symptoms have been reported to respond to prolonged proton pump inhibitor therapy, but the Hill approach to resolving these specific individual symptoms has not been widely reported in surgical literature. METHODS...

Introduction: Gastroesophageal reflux (GER) is the most common of esophageal disorder in all ages.  GER defined as passage of gastric contents into the esophagus, and GER disease (GERD), (symptoms or complications of GER), are common pediatric problems. Clinical manifestations of GERD in infants include regurgitation, irritability, choking, gagging vomiting, poor weight gain and respiratory dis...