نتایج جستجو برای: neomorphic phases

تعداد نتایج: 109108  

Journal: :Molecular Genetics & Genomic Medicine 2015

پایان نامه :وزارت علوم، تحقیقات و فناوری - پژوهشگاه دانشهای بنیادی (مرکز تحقیقات فیزیک نظری و 1387

we show that when both sources ( lepton flavor violation sources and cp-violating phases) are present, the electric dipole moment of the electron, $d_e$, receives a contribution from the phase of the trilinear $a$-term of staus, $phi_{a_ au}$. for $phi_{a_ au}=pi/2$, the value of $d_e$, depending on the ratios of the lfv mass elements, can range between zero and three orders of magnitude a...

Journal: :Development 1995
J Curtiss J S Heilig

Metamorphosis in Drosophila melanogaster requires synchronization of numerous developmental events that occur in isolated imaginal precursor tissues. The imaginal primordia are established during embryonic stages and are quiescent for much of larval life. The Arrowhead gene is necessary for establishment of proper numbers of cells within a subset of imaginal precursor tissues. Loss-of-function ...

2017
Izabella Lovas Balázs Dóra Eugene Demler Gergely Zaránd

Izabella Lovas,1 Balázs Dóra,1 Eugene Demler,2 and Gergely Zaránd1 1MTA-BME Exotic Quantum Phases “Momentum” Research Group and Department of Theoretical Physics, Budapest University of Technology and Economics, 1111 Budapest, Hungary 2Physics Department, Harvard University, Cambridge, Massachusetts 02138, USA (Received 20 December 2016; revised manuscript received 3 March 2017; published 22 Ma...

Journal: :The EMBO journal 2007
Ryuki Hirano Heidrun Interthal Cheng Huang Tomonori Nakamura Kimiko Deguchi Kunho Choi Meenakshi B Bhattacharjee Kimiyoshi Arimura Fujio Umehara Shuji Izumo Jennifer L Northrop Mustafa A M Salih Ken Inoue Dawna L Armstrong James J Champoux Hiroshi Takashima Cornelius F Boerkoel

Tyrosyl-DNA phosphodiesterase 1 (Tdp1) cleaves the phosphodiester bond between a covalently stalled topoisomerase I (Topo I) and the 3' end of DNA. Stalling of Topo I at DNA strand breaks is induced by endogenous DNA damage and the Topo I-specific anticancer drug camptothecin (CPT). The H493R mutation of Tdp1 causes the neurodegenerative disorder spinocerebellar ataxia with axonal neuropathy (S...

2016
Robson Scheffer-Teixeira Adriano Bl Tort

Phase-amplitude coupling between theta and multiple gamma sub-bands is a hallmark of hippocampal activity and believed to take part in information routing. More recently, theta and gamma oscillations were also reported to exhibit phase-phase coupling, or n:m phase-locking, suggesting an important mechanism of neuronal coding that has long received theoretical support. However, by analyzing simu...

Journal: :Physical review. B, Condensed matter 1995
Ethridge Erwin Pickett

A metastable phase of NbN with superconducting T c =16.4 K was reported recently by Treece and collaborators. The reported structure of the thin film sample deviates from the rocksalt (B1) NbN structure with 25% ordered vacancies on each sublattice (space group Pm3m) and a lattice constant of 4.442Å. Using full potential electronic structure methods, we contrast the electronic structure with th...

2016
Beth G. Gibson Michael D. Briggs

The large chondroitin sulphated proteoglycan aggrecan (ACAN) is the most abundant non-collagenous protein in cartilage and is essential for its structure and function. Mutations in ACAN result in a broad phenotypic spectrum of non-lethal skeletal dysplasias including spondyloepimetaphyseal dysplasia, spondyloepiphyseal dysplasia, familial osteochondritis dissecans and various undefined short st...

Journal: :Cancer discovery 2013
Rob A Cairns Tak W Mak

Heterozygous mutations in catalytic arginine residues of isocitrate dehydrogenases 1 and 2 (IDH1 and IDH2) are common in glioma, acute myeloid leukemia, chondrosarcoma, cholangiocarcinoma, and angioimmunoblastic T-cell lymphoma. The mutant enzymes acquire a neomorphic activity that converts α-ketoglutarate (α-KG) to D-2-hydroxyglutarate (D2HG), a rare metabolite. In cells and tissues expressing...

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