The aqueous-ethanol extract of the Hypericum perforatum (Hp-Ext.) was studied for its possible effect on Naloxone (NLX)-precipitated Opium withdrawal physical signs in rats. Purified Opium was used to induce dependence in rats using 8 days treatment schedule. The animals received Opium extract orally twice daily at 09:00 hrs and 19:00 hrs starting with initial dose of 80 mg/kg (equivalent to 8 ...

The aqueous-ethanol extract of the Hypericum perforatum (Hp-Ext.) was studied for its possible effect on Naloxone (NLX)-precipitated Opium withdrawal physical signs in rats. Purified Opium was used to induce dependence in rats using 8 days treatment schedule. The animals received Opium extract orally twice daily at 09:00 hrs and 19:00 hrs starting with initial dose of 80 mg/kg (equivalent to 8 ...

in traditional medicine,some plants are used as analgesic.the aim of this investigation was to evaluate the analgesis effect of melilotus officinalis.which is used traditionally to relieve rheumatic pain,migrian and as anti-inflammatory agent.for this purpose different doses of the suxheleted and percolated extract of melilotus officinalis,were injected intraperiotoneally to mice and the analge...

Introduction: Methadone has been used as a drug to detoxify opioid tolerance. Naloxane precipitated morphine withdrawal behaviours were attenuated by venlafaxine as an antidepressant. On the contrary, after detoxifying the opioids, spontaneous withdrawal syndrome may occur with pain sensitivity. Therefore the present study aimed to examine the effects of chronic methadone (70 mg/kg, in dr...

Technology transfer for environmental 29 purposes renovation of water and gas pipelines Kajasn Toomanian Migraine in children and adolescents 33 Ali Gorji Avicenna The Iranian journal of science and culture Letter from the editor Travelling of ideas as well as scientific and cultural interaction and interpenetration recurs in human history as naturally and persistently as the emigration of bird...

ziziphora tenuior has been used in iranian folk medicine as an analgesic and for treament of digestive diseases.this study was designed to investigate the antinociceptive effects of hydroalcoholic extract of z. tenuior on visceral pain and its possible involvement in opioidergic and serotoninergic systems in male albino n-mri mice. antinociceptive effect of was determined by writhing test as a ...

introduction: feverfew (tanacetum parthenium) (t.p.) is widely used in folk medicine to treat many diseases. we reported the analgesic effect of t.p. flower and leaf previously. present study is designed to find the mechanism underlying the anti-nociceptive effect of the aqueous extract of t.p. flower. method: based on our previous study, the dose 50 mg/kg i.p. of the t.p. aqueous extract had a...

ziziphora tenuior has been used in iranian folk medicine as an analgesic and for treament of digestive diseases.this study was designed to investigate the antinociceptive effects of hydroalcoholic extract of z. tenuior on visceral pain and its possible involvement in opioidergic and serotoninergic systems in male albino n-mri mice. antinociceptive effect of was determined by writhing test as a ...

introduction: methadone has been used as a drug to detoxify opioid tolerance. naloxane precipitated morphine withdrawal behaviours were attenuated by venlafaxine as an antidepressant. on the contrary, after detoxifying the opioids, spontaneous withdrawal syndrome may occur with pain sensitivity. therefore the present study aimed to examine the effects of chronic methadone (70 mg/kg, in drinking...

Bone fractures usually happen during car accident and sport trauma. Different factors influence bone healing such as malnutrition and smoking. Apart from addiction which is an important individual, social, and cultural problems morphine has several effects on body physiology and immune system .This study is performed to assess the effect of morphine dependency on bone healing and has not been r...