behçet’s ‎ disease is a multisystem vasculitis. its neurological involvement mostly includes parenchymal and non-parenchymal central nervous system manifestations. peripheral nervous system presentations are rare. a 32-yr-old male patient who fulfilled the international study group criteria for behçet’s disease, referred to our center with walking difficulty and repeated falling downs. neurolog...

Systemic sclerosis (systemic scleroderma) is a chronic connective tissue disease of unknown etiology that causes widespread microvascular damage and excessive deposition of collagen in the skin and internal organs. Raynaud phenomenon and scleroderma (hardening of the skin) are hallmarks of the disease. The typical patient is a young or middle-age woman with a history of Raynaud phenomenon who p...

BACKGROUND Langerhans cell histiocytosis (LCH) is a rare disease with abnormal accumulation of the dendritic Langerhans cells. In the localized form (single system), the disease is self-limiting but in the cases of multisystem disease, one third of the patients develop organ dysfunction with poor prognosis. The aim of this study was to examine the role of p53 and vascular endothelial growth fac...

The aim of the study is to present the experience of children diagnosed with Langerhans cell histiocytosis (LCH) at our center. Medical records of children with LCH were screened in terms of gender, age at diagnosis, clinical findings, risk groups, treatment modalities and outcome. The study included 9 patients with a median age of 22 months. The most common clinical finding was bone lesions (%...

Rheumatoid Arthritis (RA) is a multisystem disorder, which causes significant morbidity. An early diagnosis of RA is essential to prevent the development of irreversible bone and joint changes. The disease has characteristic clinical features, but an early evaluation of the quantum of disease may be difficult with plain radiography alone. Recent developments in the imaging of RA have contribute...