نتایج جستجو برای: multidrug resistance 1 gene

تعداد نتایج: 3830621  

Journal: :Molecular medicine reports 2014
Ke Zhang Xian Wang Hongyan Wang

The development of tumor cell drug resistance is the primary reason for treatment failure in lung cancer chemotherapy. Therefore, overcoming multidrug resistance is currently an urgent issue to be addressed in lung cancer treatment. Sunitinib is a tyrosine kinase inhibitor with confirmed inhibitory effects on tumor growth and metastasis; however, the effects of sunitinib and mechanisms of actio...

Journal: :iranian journal of public health 0
seshadhri shanmugapriya school of biotechnology, dr. g.r. damodaran college of science , india. thangavel senthilmurugan school of biotechnology, dr. g.r. damodaran college of science , india. thangavelu thayumanavan school of biotechnology, dr. g.r. damodaran college of science , india.

yersinia enterocolitica is rapidly emerging worldwide as an enteric pathogen and has become a major cause of diarrhea even in developed countries. the aim of this study was to characterize and genetic diversity analysis among y. enterocolitica strains isolated from fish and chicken sources.from 44 strains, 55% (24 strains) found to be positive for y. enterocolitica by colony morphology, biochem...

Journal: :Indian Journal of Hematology and Blood Transfusion 2007

Journal: :European journal of pharmacology 2011
Bu Tong Sun Li Hua Zheng Yong Li Bao Chun Lei Yu Yin Wu Xiang Ying Meng Yu Xin Li

Multidrug resistance is a serious obstacle encountered in cancer treatment. Since drug resistance in human cancer is mainly associated with overexpression of the multidrug resistance gene 1 (MDR1), the promoter of the human MDR1 gene may be a target for multidrug resistance reversion drug screening. In the present study, HEK293T cells were transfected with pGL3 reporter plasmids containing the ...

ژورنال: Iranian Biomedical Journal 2015
Habibzade, Seyyed Mahmood , Mehdipour Moghaddam, Mohammad Javad , Mirbagheri, Adeleh Alsadat , Salehi, Zivar,

Background: Extended spectrum beta lactamases (ESBLs) are an important cause of transferable multidrug resistance (MDR) in gram-negative bacteria. The most described ESBL genes are generally found within integron-like structures as mobile genetic elements. The aim of this study was to identify the accompanying of class 1 integrons and ESBLs in the MDR E. coli isolates. Methods: Susceptibility t...

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