Most scholars regard mixed connective tissue disease (MCTD) to be a separate illness, whereas some suggest it might precursor distinct disease, such as SLE, SSc, or overlap syndrome. There are no clinical symptoms of MCTD, and presentations vary greatly across individuals. Since the first description, categorization entity has been debated, particularly because individuals with U1 small nuclear...

BACKGROUND Liver disease is rare in the course of mixed connective tissue disease. Most commonly liver steatosis or elevated liver function tests are reported and only a few cases of mixed connective tissue disease associated with autoimmune hepatitis were described. CASE PRESENTATION We report a case of an 11-year old boy with hepatitis on admission to the hospital and symptoms and signs of ...

Normal Pressure hydrocephalus (NPH) is characterized by gait apraxia, urinary incontinence, and dementia. Mixed connective tissue disease (MCTD) is an autoimmune connective tissue disease that has never been reported to cause NPH. Our patient was a 67-year man with a one-year history of gradual worsening gait and balance, urinary urgency with urge incontinence and decreased short-term memory. P...

Cutaneous mucinosis is a group of conditions involving an accumulation of mucin or glycosaminoglycan in the skin and its annexes. It is described in some connective tissue diseases but never in association with mixed connective tissue disease. This report concerns two cases of cutaneous mucinosis in patients with mixed connective tissue disease in remission; one patient presented the papular fo...