Ethylene glycol (EG) and methanol poisoning can cause life-threatening complications. Toxicity of EG and methanol is related to the production of toxic metabolites by the enzyme alcohol dehydrogenase (ADH), which can lead to metabolic acidosis, renal failure (in EG poisoning), blindness (in methanol poisoning) and death. Therapy consists of general supportive care (e.g. intravenous fluids, corr...

introduction: alcohol poisoning is one of the main preventable causes of death, disability, and injury in many societies. ethanol and methanol are the most prevalent kinds of alcohol used. there is no any exact reports of alcohol poisoning and its outcome in iranian society. therefore, the present study was assessed the status of alcohol poisoning and its outcome in referees to the emergency de...

Background Formic acid (formate) is the main reason for toxicity and death through methanol poisoning. The simultaneous determination of methanol, ethanol, and formate in the body can help to discover the cause of death and is useful in the diagnosis of acute methanol poisoning. The measurement of formate is not yet available in Iran. With regard to the increasing rate of methanol poisoning and...

therapy. Since Ben nett's work , in the epidemic of methanol poisoning in Atlanta in 1953, the major therapeutic advance In the treatment of methanol poisoning has been the application of dialysis therapy with special attention focused on extracorporeal treatment. In none of the 11 patients studied here was hemodialysis used. Peritoneal dialysis was U1 evaluated and attempts were made to follow...

Epidemics of methanol poisoning happen across the globe. There are prognostic factors associated with morbidity or mortality from methanol poisoning. Recently we have compared retrospective observational case series of methanol-poisoned patients from Norway (1979 and 2002-2005), Estonia (2001) and Tunisia (2003/2004), and patients from two different centers in Iran (Teheran 2004-2009 and Mashha...

although antidote development should proceed in an orderly fashion from observation, to experimental and safety studies, to clinical trials, this sequence is not always precisely followed. the development of fomepizole as an antidote for toxic alcohol and glycol poisoning is an example of how this may not be the case. interest in the development of fomepizole was spurred in the 1960s. shortly t...

background: toxic alcohol poisonings are responsible for high mortality and morbidity in russia. this study was aimed to evaluate the trends of harmful ethanol (etoh) drinking as well as methanol (meoh), isopropanol (ipa) and ethylene glycol (eg) poisonings in the middle urals region of russia. methods: in this retrospective study, the medical records of patients poisoned with meoh, ipa and eg ...

Self-induced poisoning with chemicals is one of the most commonly used suicide methods. Suicide attempts using massive pure sodium ferrocyanide and methanol are rare. This article discusses the management of acute intentional self-poisoning using sodium ferrocyanide and methanol. We present a case of acute self-induced poisoning using sodium ferrocyanide and methanol admitted to our hospital 2 ...

background: in this study we sought to investigate clinical findings (with a focus on neurologic effects) and also to analyze outcomes of a series of patients with methanol poisoning admitted to two poisoning treatment centers in tehran, iran. methods: in this prospective cross-sectional study, methanol-poisoned patients admitted to departments of forensic medicine and toxicology of loghman hak...

introduction methanol is a highly toxic substance and methanol poisoning results in severe health situations. methanol poisoning occurs when it is consumed by various methods such as orally, by inhalation, and transdermally. transdermal poisoning is rarely seen and causes severe health complications. conclusions methanol poisoning presents to the emergency department in our country with many di...